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GSK369796显示抗疟活性，3D7菌株的IC50值为11.2nM，HB3菌株为12.6nM，K1菌株为17.6nM.
| In vitro | DMSO | 82 mg/mL (191.23 mM) | |
| Water | 38 mg/mL (88.62 mM) | ||
| Ethanol | 10 mg/mL (23.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.32 mL | 116.61 mL | 233.21 mL |
| 0.5 mM | 4.66 mL | 23.32 mL | 46.64 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 428.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13455 |
|---|---|
| M. Wt | 428.79 |
| Formula | C20H24Cl3N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1010411-21-8 |
| Synonyms | GSK 369796, GSK-369796 |
| SMILES | CC(C)(C)NCC1=C(C=C(C=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.Cl.Cl |
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