NMS-873

Name: NMS-873
SKU: A12377

目录号: A12377

p97 抑制剂

Product Citations (1)

NMS-873 Chemical Structure

CAS NO. 1418013-75-8

NMS-873是一种有效且特异的ATPase VCP/p97小分子变构抑制剂（IC50?0.03 uM），通过高通量筛选得以鉴定。

库存：现货

规格	价格	数量
5 mg	￥ 490.00
10 mg	￥ 840.00
25 mg	￥ 1,750.00
50 mg	￥ 3,150.00
10mM * 1mL in DMSO	￥ 525.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

NMS-873是一种有效且特异的ATPase VCP/p97小分子变构抑制剂（IC50?0.03 uM），通过高通量筛选得以鉴定。

靶点信息

p97
30 nM

溶解度 *

In vitro	DMSO	98 mg/mL (188.22 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.21 mL	96.03 mL	192.06 mL
0.5 mM	3.84 mL	19.21 mL	38.41 mL
1 mM	1.92 mL	9.6 mL	19.21 mL
5 mM	0.38 mL	1.92 mL	3.84 mL

*The above data is based on the productmolecular weight 520.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12377
作用机制	Inhibitor (抑制剂)
M. Wt	520.67
Formula	C27H28N4O3S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1418013-75-8
Synonyms	NMS873, NMS 873
SMILES	CC1=C(C=CC(=C1)OCC2=NN=C(N2C3=CN=CC=C3)SC4CCCC4)C5=CC=C(C=C5)S(=O)(=O)C