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Temanogrel
Catalog No. A17094 5-HT(2A) receptor 激动剂Temanogrel，也称为APD791，是一种高度选择性的5-羟基色胺2A受体反向激动剂，正在开发中，用于治疗动脉血栓形成。 了解更多 -
LY 334370 hydrochloride
Catalog No. A17027 5-HT1F 激动剂LY 334370 hydrochloride是一种选择性的5-HT1F受体激动剂（Ki值为1.87、16.4，> 100 (IC50)）。CAS：199673-74-0（LY 334370盐酸盐）；182563-08-2（LY 334370游离碱） 了解更多 -
LY 344864 racemate
Catalog No. A17015 -
Volinanserin
Catalog No. A17115 -
Eptapirone (F-11440)
Catalog No. A18338 5-HT1A receptor agonistEptapirone is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone. 了解更多 -
Dolasetron
Catalog No. A17595 5-HT3 receptor antagonistDolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. 了解更多 -
Nefazodone hydrochloride
Catalog No. A17622 5-HT2 receptors inhibitorNefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多 -
Dolasetron Mesylate
Catalog No. A17729 5-HT3 receptor antagonistDolasetron mesylate is a selective 5-HT3 receptor antagonist. 了解更多 -
Alprenolol hydrochloride
Catalog No. A17781 5-HT1A receptor antagonistAlprenolol (hydrochloride) is a non-selective beta blocker as well as 5-HT1A receptor antagonist. 了解更多 -
Alosetron (Hydrochloride(1:X))
Catalog No. A11309 Serotonin 5HT3-receptor antagonistAlosetron Hydrochloride(1:X) (GR 68755 Hydrochloride(1:X)) is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. 了解更多 -
SB 258585 HCl
Catalog No. A14026 5-HT6 serotonin receptor 拮抗剂SB 258585 hydrochloride是一种选择性和有效的SR-6拮抗剂。该化合物显示出比其他5-羟色胺受体亚型高160倍的选择性。 了解更多 -
Granisetron
Catalog No. A15096 -
LY 344864
Catalog No. A15148 -
WAY-100635 maleate salt
Catalog No. A15282 -
Ricasetron
Catalog No. A15499 -
LY278584
Catalog No. A15500 -
Lerisetron
Catalog No. A15501 -
SB271046
Catalog No. A15438 -
Pimavanserin (ACP-103)
Catalog No. A14434 5-HT2A receptor 激动剂Pimavanserin (ACP-103)是一种有效的选择性5-HT2A受体反向激动剂，在基于细胞的功能测定中，平均pIC50为8.7。 了解更多 -
Ketanserin tartrate
Catalog No. A13664 5HT2A 拮抗剂Ketanserin tartrate是一种选择性的5-HT receptor拮抗剂。Ketanserin tartrate 也抑制 hERG 电流 (IhERG)，IC50 为 0.11 μM。 了解更多 -
WAY 181187
Catalog No. A14163 -
Flopropione
Catalog No. A16550 5-HT1A receptor antagonist/COMT inhibitorFlopropione是5-HT1A受体拮抗剂，也是儿茶酚-邻甲基转移酶（COMT）抑制剂。 了解更多 -
Donitriptan
Catalog No. A13145 5-HT1B/1D receptors agonistDonitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively. 了解更多 -
Deramciclane
Catalog No. A13011 5-HT2A and 5-HT2C receptors antagonistDeramciclane has a high affinity for 5-HT2A and 5-HT2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT2C receptors without direct stimulatory agonist. 了解更多 -
lumateperone Tosylate
Catalog No. A12279 5-HT2A receptor antagonistLumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). 了解更多 -
5-HT4 antagonist 1
Catalog No. A12268 5-HT4 receptor antagonist5-HT4 antagonist 1 is a 5-HT4 receptor antagonist with a pKi of 9.6. 了解更多 -
PRX933 hydrochloride
Catalog No. A12261 5-HT2c receptor agonistPRX933 hydrochloride is a 5-HT2c receptor agonist extracted from patent WO 2014140631 A1. 了解更多 -
Ziprasidone hydrochloride monohydrate
Catalog No. A11008 5-HT (serotonin) and dopamine receptor antagonistZiprasidone hydrochloride monohydrate (CP 88059 hydrochloride monohydrate) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多 -
Pancopride
Catalog No. A12967 5-HT3 receptor antagonistPancopride is a new potent and selective 5-HT3 receptor antagonist. 了解更多 -
Lesopitron dihydrochloride
Catalog No. A12950 5-HT1A receptor agonistLesopitron dihydrochloride is a full and selective 5-HT1A receptor agonist with IC50 of 125 nM in rat hippocampal membranes. 了解更多 -
SB 271046 Hydrochloride
Catalog No. A11573 5-HT6 receptor antagonistSB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. 了解更多 -
WAY-100635 Maleate
Catalog No. A16787 5-HT1A receptor antagonistWAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. 了解更多 -
Ziprasidone hydrochloride
Catalog No. A16790 5-HT (serotonin)/dopamine receptor antagonistZiprasidone Hcl(CP-88059 Hcl) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. 了解更多 -
Sarpogrelate hydrochloride
Catalog No. A17295 5-HT2 antagonistSarpogrelate hydrochloride (MCI-9042), a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. 了解更多 -
Vortioxetine
Catalog No. A21266 5-HT1A/5-HT1B/5-HT3A/5-HT7 receptor/SERT inhibitorVortioxetine is a inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT, with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. 了解更多 -
WAY 163909
Catalog No. A21282 5-HT(2C) receptor agonistWAY 163909 is a potent and selective 5-HT(2C) receptor agonist with a Ki of 10.5??1.1 nM. 了解更多 -
SB 242084 hydrochloride
Catalog No. A21349 5-HT2C receptor antagonistSB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. 了解更多 -
Masupirdine mesylate
Catalog No. A21409 5-HT6 receptor antagonistMasupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). 了解更多 -
Nelotanserin
Catalog No. A21506 5-HT2A inverse agonistNelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. 了解更多
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