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GDC-0927 Racemate

Catalog No. A21507
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estrogen receptor degrader

GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. 了解更多

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Elacestrant

Catalog No. A12244
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Estrogen receptor degrader

Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. 了解更多

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PROTAC ERRα Degrader-1

Catalog No. A18910
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ERRα Degrader

PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader. 了解更多

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PROTAC ER Degrader-3

Catalog No. A18519
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PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab). 了解更多

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GDC-0810 (Brilanestrant)

Catalog No. A15958
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Estrogen receptor degrader

GDC-0810 (Brilanestrant)是一种口服可生物利用的选择性雌激素受体降解剂（SERD），在耐他莫昔芬的乳腺癌异种移植物中表现出强大的活性。了解更多

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