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搜索结果：“gdc 0084”

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GDC-0339

Catalog No. A20920
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Pim kinase inhibitor

GDC-0339 is a potent, orally bioavailable and well tolerated pan-Pim kinase inhibitor, with Kis of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. GDC-0339 is discovered as a potential treatment of multiple myeloma. 了解更多

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C188-9

Catalog No. A16804
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STAT3 抑制剂

C188-9是一种有效的STAT3抑制剂，它以高亲和力（KD = 4.7±0.4 nM）与STAT3结合。C188-9在小鼠中具有良好的耐受性，显示出良好的口服生物利用度，并且集中在肿瘤中。了解更多

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PF-06700841 P-Tosylate

Catalog No. A21652
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dual JAK1/TYK2 inhibitor

PF-06700841 P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. 了解更多

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PF-06700841 tosylate

Catalog No. A17176
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JAK1 and TYK2 抑制剂

PF-06700841 tosylate是JAK1和TYK2激酶的抑制剂。了解更多

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