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搜索结果：“gdc 0084”

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G-479

Catalog No. A14380
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MEK 抑制剂

G-479是有效的MEK抑制剂。在许多方面，极性分布在整个分子中的G-479被证明具有比GDC-0623更高的生物活性。了解更多

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Cobimetinib (R-enantiomer)

Catalog No. A15051
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MEK 抑制剂

Cobimetinib R-enantiomer是Cobimetinib的R对映异构体，Cobimetinib是一种有力的，高选择性的促分裂原活化蛋白激酶（MEK1/2）抑制剂。了解更多

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Cobimetinib (racemate)

Catalog No. A15050
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MEK 抑制剂

Cobimetinib (racemate)是一种有效的，高度选择性的MEK1/2抑制剂。了解更多

Product Citations (2)

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- Yuki Shimizu, .et al. Acquired resistance to BRAF inhibitors is mediated by BRAF splicing variants in BRAF V600E mutation-positive colorectal neuroendocrine carcinoma, Cancer Lett, 2022, Sep 1;543 PMID: 35724767
- Chun-Yu Liu, .et al. Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells, Cancers (Basel), 2019, Jan 17;11(1) PMID: 30658422

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