“No”的搜索结果

产品 651 到 700 共 2783个

每页
页面:
  1. 12
  2. 13
  3. 14
  4. 15
  5. 16

设置降序顺序
  1. 2614W94

    Catalog No. A19341
    Quick View
    monoamine oxidase-A inhibitor
    2614W94 is a selective, reversible inhibitor of monoamine oxidase-A with a competitive mechanism of inhibition and IC50 of 5 nM and Ki of 1.6 nM with serotonin as substrate. 了解更多
  2. ONO-8590580

    Catalog No. A19337
    Quick View
    GABAA α5 modulator
    ONO-8590580 is a GABAA α5 negative allosteric modulator. 了解更多
  3. Inarigivir soproxil

    Catalog No. A19335
    Quick View
    innate immunity agonist
    Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. 了解更多
  4. Procyanidol B4

    Catalog No. A19331
    Quick View
    Procyanidol B4 ((-)-Procyanidin B4) is a flavanol, isolated from Litchi chinensis. Anti-inflammatory properties. 了解更多
  5. SAHA chloroalkane T1

    Catalog No. A19324
    Quick View
    SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1. 了解更多
  6. Paliroden

    Catalog No. A19323
    Quick View
    Paliroden is an orally bioactive neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines, used for treatment of Alzheimer's Disease and Parkinson's. 了解更多
  7. KU-32

    Catalog No. A19321
    Quick View
    Hsp90 inhibitor
    KU-32 is a novel, novobiocin-based Hsp90 inhibitor that can protect against neuronal cell death. 了解更多
  8. Praliciguat

    Catalog No. A19315
    Quick View
    guanylate cyclase stimulator
    Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM. 了解更多
  9. G-1

    Catalog No. A19310
    Quick View
    GPR30 agonist
    G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM. 了解更多
  10. Quilseconazole

    Catalog No. A19305
    Quick View
    fungal Cyp51 inhibitor
    Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes. 了解更多
  11. Aminomalonic acid

    Catalog No. A19289
    Quick View
    Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. 了解更多
  12. NCX1022

    Catalog No. A19275
    Quick View
    NCX1022 is an NO-releasing derivative of Hydrocortisone, which is the most widely used anti-inflammatory drug for the treatment of skin inflammation. 了解更多
  13. Gadopentetic acid

    Catalog No. A19262
    Quick View
    paramagnetic contrast agent
    Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies. The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI. 了解更多
  14. Adavivint

    Catalog No. A19257
    Quick View
    Wnt signaling inhibitor
    Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. 了解更多
  15. Alobresib

    Catalog No. A19246
    Quick View
    BET bromodomain inhibitor
    Alobresib (GS-5829) is a BET bromodomain inhibitor, which represents a highly effective therapeutics agent against recurrent/chemotherapy resistant uterine serous carcinoma (USC) overexpressing c-Myc. 了解更多
  16. Sotirimod

    Catalog No. A19244
    Quick View
    immunostimulant
    Sotirimod is an immunostimulant, and can potentially treat for actinic keratosis. 了解更多
  17. T-00127_HEV1

    Catalog No. A19240
    Quick View
    PI4KB inhibitor
    T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM. 了解更多
  18. Nomegestrol

    Catalog No. A19235
    Quick View
    full progesterone receptor agonist
    Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. 了解更多
  19. Delgocitinib

    Catalog No. A19234
    Quick View
    JAK inhibitor
    Delgocitinib is a novel and specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. 了解更多
  20. 6-Aminochrysene

    Catalog No. A19229
    Quick View
    6-Aminochrysene (6-Aminochrysene) is an aromatic amine used as a chemotherapeutic agent in the treatment of splenomegaly, myeloid leukemia, and breast cancer. 了解更多
  21. IMD-0560

    Catalog No. A19224
    Quick View
    IκB kinase β inhibitor
    IMD-0560 is a novel IκB kinase β inhibitor. 了解更多
  22. eIF4A3-IN-2

    Catalog No. A19219
    Quick View
    eIF4A3 inhibitor
    eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. 了解更多
  23. Endovion

    Catalog No. A19215
    Quick View
    anion channel inhibitor
    Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor. 了解更多
  24. 1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine

    Catalog No. A19212
    Quick View
    1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside. 了解更多
  25. KZR-504

    Catalog No. A19210
    Quick View
    LMP2 inhibitor
    KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 is of interest for the treatment of autoimmune disease. 了解更多
  26. 13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide

    Catalog No. A19207
    Quick View
    derivative of Retinoic acid
    13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide is a derivative of Retinoic acid. 了解更多
  27. 3'-Azido-3'-deoxy-5-methylcytidine

    Catalog No. A19200
    Quick View
    XMRV inhibitor
    3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 了解更多
  28. GPR40 agonist 1

    Catalog No. A19192
    Quick View
    GPR40 full agonist
    GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively. 了解更多
  29. m-Coumaric acid

    Catalog No. A19189
    Quick View
    m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. 了解更多
  30. Stanolone benzoate

    Catalog No. A19184
    Quick View
    Stanolone benzoate (Androstanolone benzoate) is a synthetic androgen and anabolic steroid. 了解更多
  31. MC-Alkyl-Hydrazine Modified MMAF

    Catalog No. A19179
    Quick View
    MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine. 了解更多
  32. Cholestenone

    Catalog No. A19178
    Quick View
    Cholestenone is the intermediate oxidation product of cholesterol. 了解更多
  33. 2-Iminobiotin

    Catalog No. A19175
    Quick View
    nitric oxide synthases inhibitor
    2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively. 了解更多
  34. Nicotinic acid mononucleotide

    Catalog No. A19173
    Quick View
    Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase. 了解更多
  35. Suberylglycine

    Catalog No. A19171
    Quick View
    Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid. 了解更多
  36. N-Glycolylneuraminic acid

    Catalog No. A19166
    Quick View
    N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs). 了解更多
  37. Guanidinosuccinic acid

    Catalog No. A19165
    Quick View
    Guanidinosuccinic acid is a nitrogenous metabolite isolated in excess from serum and urine. 了解更多
  38. PEG4-aminooxy-MMAF

    Catalog No. A19160
    Quick View
    PEG4-aminooxy-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4. 了解更多
  39. 2,3-Diaminopropionic acid

    Catalog No. A19153
    Quick View
    2, 3-Diaminopropionic acid is a metabolite of b-oxalyl-L-a, b-diaminopropionic acid a neurotoxic amino acid (ODAP). 了解更多
  40. LHVS

    Catalog No. A19147
    Quick View
    cysteine protease inhibitor
    LHVS is a potent, non-selective cysteine protease inhibitor. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. 了解更多
  41. (S)-b-aminoisobutyric acid

    Catalog No. A19146
    Quick View
    (S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. 了解更多
  42. Nitroaspirin

    Catalog No. A19145
    Quick View
    Nitroaspirin (NCX 4016) is a nitric oxide (NO) donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin (NCX 4016) has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor of COX-1. 了解更多
  43. Pomalidomide-PEG3-C2-NH2

    Catalog No. A19141
    Quick View
    E3 ligase ligand-linker conjugate
    Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. 了解更多
  44. 2-Hydroxybutyric acid

    Catalog No. A19139
    Quick View
    2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite. 了解更多
  45. Vonoprazan free base

    Catalog No. A18007
    Quick View
    potassium-competitive acid blocker
    Vonoprazan (TAK-438 free base) is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM. 了解更多
  46. (R)-Serine

    Catalog No. A17978
    Quick View
    NMDA glutamate receptor co-agonist
    (R)-Serine, an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. 了解更多
  47. Cephradine monohydrate

    Catalog No. A17949
    Quick View
    Cephradine monohydrate (Cefradine monohydrate) is a first generation cephalosporin, which is active against a wide range of Gram positive and Gram-negative bacteria. 了解更多
  48. 2-Methylhexanoic acid

    Catalog No. A17815
    Quick View
    2-methylhexanoic acid is a medium-chain fatty acid and is used as flavouring. 了解更多
  49. Hydroquinine

    Catalog No. A17533
    Quick View
    Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride. 了解更多
  50. RBC8

    Catalog No. A16681
    Quick View
    Ral GTPase inhibitor
    RBC8 is a novel small molecule inhibitor of Ral GTPase; has IC50 of 3.5 μM in H2122 cell and 3.4 μM in H358 cell. 了解更多

产品 651 到 700 共 2783个

每页
页面:
  1. 12
  2. 13
  3. 14
  4. 15
  5. 16

设置降序顺序
Rewards