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(-)-Menthol
Catalog No. A15621 (-)-Menthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i. Antitumor activity. 了解更多 -
N6-Etheno 2'-deoxyadenosine
Catalog No. A13280 biomarkerN6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues. 了解更多 -
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N-[(4-Aminophenyl)methyl]adenosine
Catalog No. A12659 Adenosine receptor inhibitorN-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5??-Nucleotidase. IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor 了解更多 -
GSK2292767
Catalog No. A16564 PI3Kδ inhibitorGSK2292767 is a potent and selective inhibitor of phosphatidylinositol 3-kinase δ (PI3Kδ; Ki = 79 pM). GSK2292767 is >100-fold selective for PI3Kδ over a panel of 250 kinases. 了解更多 -
Mitoquinone mesylate
Catalog No. A21693 Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage. 了解更多 -
Eprinomectin
Catalog No. A21657 Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity. 了解更多 -
Banoxantrone D12
Catalog No. A21443 Banoxantrone D12 (AQ4N D12) is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多 -
Banoxantrone D12 dihydrochloride
Catalog No. A21438 Banoxantrone D12 dihydrochloride (AQ4N D12 dihydrochloride) is the deuterium labeled banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多 -
Duocarmycin A
Catalog No. A21433 Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3?? end of AT-rich sequences in the DNA. 了解更多 -
Banoxantrone dihydrochloride
Catalog No. A21432 Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. 了解更多 -
Ionomycin calcium
Catalog No. A21370 Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. 了解更多 -
Frentizole
Catalog No. A21335 Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction. 了解更多 -
4-Azido-L-phenylalanine
Catalog No. A21332 4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 了解更多 -
Pozanicline
Catalog No. A21318 Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2* nAChRs (Ki=16 nM) and shows high selectivity for α6β2* and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM. 了解更多 -
Fexinidazole
Catalog No. A21274 Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei. 了解更多 -
Succinobucol
Catalog No. A21251 Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. 了解更多 -
Cariprazine
Catalog No. A21202 D3 receptor and D2 receptor partial agonistCariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). 了解更多 -
Miquelianin
Catalog No. A21196 Miquelianin is one of the flavonoids of St. John's wort (Hypericum perforatum L.) with antidepressant activity. 了解更多 -
L-Theanine
Catalog No. A21167 L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. 了解更多 -
Nilutamide
Catalog No. A21165 Nilutamide (Nilandron) is a non-steroidal anti-androgen drug proposed in the treatment of metastatic prostatic carcinoma. 了解更多 -
Avarofloxacin
Catalog No. A21045 Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia. 了解更多 -
Ulipristal acetate
Catalog No. A21041 progesterone receptor modulatorUlipristal (acetate) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. 了解更多 -
Ombrabulin hydrochloride
Catalog No. A21040 Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. 了解更多 -
(R)-Oxiracetam
Catalog No. A21023 (R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant. 了解更多 -
Gemilukast
Catalog No. A21021 CysLT1/CysLT2 antagonistGemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. 了解更多 -
Tirabrutinib
Catalog No. A21019 BTK inhibitorTirabrutinib (ONO-4059) is a highly selective, orally bioavailable BTK inhibitor with an IC50 of 2.2 nM. 了解更多 -
YF-2
Catalog No. A21018 histone acetyltransferase activatorYF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease. 了解更多 -
N6-Cyclohexyladenosine
Catalog No. A21008 A1 receptor agonistN6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). 了解更多 -
G-418 disulfate
Catalog No. A21002 G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. 了解更多 -
GSK2795039
Catalog No. A20998 NOX2 inhibitorGSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 reduces apoptosis. 了解更多 -
2'-Deoxycytidine hydrochloride
Catalog No. A20995 2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. 了解更多 -
(+)-Phenserine
Catalog No. A20993 cholinesterase noncompetitive inhibitor(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多 -
Lifirafenib
Catalog No. A20988 Raf/EGFR inhibitorLifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. 了解更多
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