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Anandamide
Catalog No. A21835 immune modulatorAnandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). 了解更多 -
Nomegestrol acetate
Catalog No. A21829 progesterone receptor agonistNomegestrol acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors. 了解更多 -
Taribavirin hydrochloride
Catalog No. A21810 inosine monophosphate dehydrogenase inhibitorTaribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. 了解更多 -
(+)-Penbutolol
Catalog No. A21806 β-adrenoceptor antagonist(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. 了解更多 -
Thalidomide-O-amido-C3-NH2 (TFA)
Catalog No. A21801 E3 ligase ligand-linker conjugateThalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
Pimonidazole
Catalog No. A21800 Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. 了解更多 -
Mavoglurant racemate
Catalog No. A21799 mGlu5 receptor antagonistMavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. 了解更多 -
Imisopasem manganese
Catalog No. A21783 Imisopasem manganese , also known as M40403, or GC4419, is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. 了解更多 -
Kira8 Hydrochloride
Catalog No. A21780 IRE1α inhibitorKira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. 了解更多 -
Brofaromine
Catalog No. A21777 MAO inhibitorBrofaromine (CGP 11305A) is a monoamine oxidase (MAO) inhibitor with IC50 of 0.2?μM for MAO-A. 了解更多 -
Tenofovir maleate
Catalog No. A21776 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多 -
Belinostat
Catalog No. A21772 HDAC inhibitorBelinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC50 of 27 nM in HeLa cell extracts. 了解更多 -
Pomalidomide-C2-NH2 hydrochloride
Catalog No. A21768 E3 ligase ligand-linker conjugatePomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
ELX-02 sulfate
Catalog No. A21764 ELX-02 sulfate (NB-124 sulfate) is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). ELX-02 sulfate is being developed as a therapy for genetic diseases caused by nonsense mutations. 了解更多 -
ELX-02 disulfate
Catalog No. A21757 ELX-02 disulfate (NB-124 disulfate) is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). ELX-02 disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations. 了解更多 -
MELK-8a hydrochloride
Catalog No. A21751 MELK inhibitorMELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM. 了解更多 -
Nazartinib mesylate
Catalog No. A21741 covalent mutant-selective EGFR inhibitorNazartinib mesylate (EGF816 mesylate) is a novel, covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min?1 on EGFR(L858R/790M) mutant, respectively. 了解更多 -
GSK3368715 dihydrochloride
Catalog No. A21733 PRMT inhibitorGSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). 了解更多 -
MCOPPB triHydrochloride
Catalog No. A21722 nociceptin receptor agonistMCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. 了解更多 -
Methoxatin disodium salt
Catalog No. A21718 Methoxatin (disodium salt) as the cofactor in bovine plasma amine oxidase from resonance Raman spectroscopy. 了解更多 -
Guanosine 5'-diphosphate disodium salt
Catalog No. A21707 iron mobilizerGuanosine 5'-diphosphate disodium salt is a nucleoside diphosphate. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. 了解更多 -
Taranabant ((1R,2R)stereoisomer)
Catalog No. A21705 CB1 receptor inverse agonistTaranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist. 了解更多 -
Lys01 trihydrochloride
Catalog No. A21702 lysosomal autophagy inhibitorLys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. 了解更多 -
TLR7/8 agonist 1 dihydrochloride
Catalog No. A21700 TLR7/8 agonistTLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. 了解更多 -
Taranabant racemate
Catalog No. A21699 CB1 antagonist/inverse agonistTaranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1. 了解更多 -
(R)-Sulforaphane
Catalog No. A21690 Keap1/Nrf2/ARE pathway inducer(R)-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. (R)-Sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. 了解更多 -
(Z)-9-Propenyladenine
Catalog No. A21687 (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. 了解更多 -
Dasotraline hydrochloride
Catalog No. A21684 triple reuptake inhibitorDasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. 了解更多 -
3-Methoxytyramine
Catalog No. A21676 neuromodulator3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator. 了解更多 -
nor-NOHA acetate
Catalog No. A21673 Arginase inhibitornor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. 了解更多 -
Ro 41-1049 hydrochloride
Catalog No. A21672 inhibitor of monoamine oxidase-A (MAO-A)Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (MAO-A). 了解更多 -
(S,R,S)-AHPC-PEG4-NH2
Catalog No. A21671 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. 了解更多 -
Ubrogepant
Catalog No. A21670 CGRP antagonistUbrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. 了解更多 -
IFN alpha-IFNAR-IN-1 hydrochloride
Catalog No. A21667 IFN-α and IFNAR interaction inhibitorIFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). 了解更多 -
(S,R,S)-AHPC-PEG2-NH2
Catalog No. A21665 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in PROTAC technology. 了解更多 -
MK2-IN-1 hydrochloride
Catalog No. A21662 MAPKAPK2(MK2) inhibitorMK2-IN-1 hydrochloride is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode. 了解更多 -
(S,R,S)-AHPC-PEG3-NH2
Catalog No. A21660 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. 了解更多 -
Rolofylline
Catalog No. A21649 adenosine A1 receptor antagonistRolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. 了解更多 -
OT-R antagonist 2
Catalog No. A21647 OT-R antagonistOT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM). 了解更多 -
Raxatrigine hydrochloride
Catalog No. A21645 Nav1.7 sodium channel inhibitorRaxatrigine hydrochloride (GSK-1014802 hydrochloride) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor. 了解更多 -
Thalidomide-O-amido-C6-NH2 (TFA)
Catalog No. A21639 E3 ligase ligand-linker conjugateThalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多
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