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(+)-Talarozole
Catalog No. A21445 retinoic acid metabolism inhibitor(+)-Talarozole is a potent inhibitor of retinoic acid metabolism extracted from patent WO 1997049704 A1. 了解更多 -
KHS101 hydrochloride
Catalog No. A21442 KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3). 了解更多 -
EIPA hydrochloride
Catalog No. A21441 TRPP3 channel inhibitorEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also inhibits Na+/H+-exchanger (NHE) and macropinocytosis. 了解更多 -
(±)-Ibipinabant
Catalog No. A21439 CB-1 receptor antagonist(±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM. 了解更多 -
CHIR-99021 monohydrochloride
Catalog No. A21430 GSK-3α/β inhibitorCHIR-99021 monohydrochloride (CT99021 monohydrochloride) is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. 了解更多 -
NVP-BHG712 isomer
Catalog No. A21426 NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4. 了解更多 -
ATN-161 trifluoroacetate salt
Catalog No. A21412 integrin α5β1 antagonistATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. 了解更多 -
Peliglitazar racemate
Catalog No. A21411 dual α/γ PPAR activatorPeliglitazar racemate is the racemate of Peliglitazar. Peliglitazar is a novel dual α/γ PPAR activator. 了解更多 -
Sch-42495 racemate
Catalog No. A21408 NEP inhibitorSch-42495 racemate is the racemate of Sch-42495. Sch-42495 is a novel neutral metalloendopeptidase (NEP) inhibitor. Sch-42495 is the orally active ethylester prodrug of SCH 42354. 了解更多 -
Saterinone hydrochloride
Catalog No. A21402 PDE3 inhibitorSaterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor. 了解更多 -
Batefenterol
Catalog No. A21387 muscarinic receptor antagonist and β2-adrenoceptor agonistBatefenterol (GSK961081;TD-5959) is a novel muscarinic receptor antagonist and β2-adrenoceptor agonist; displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor with Ki values of 1.4, 1.3 and 3.7 nM, respectively. 了解更多 -
Foliglurax monohydrochloride
Catalog No. A21384 glutamate receptor 4 modulatorFoliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect. 了解更多 -
PF-00446687
Catalog No. A21382 MC4R agonistPF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12????1 nM. Pf-446687 is brain penetrant. 了解更多 -
Exendin-4 Acetate
Catalog No. A21378 glucagon-like peptide-1 receptor agonistExendin-4 Acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多 -
Atipamezole
Catalog No. A21363 α2-adrenoceptor antagonistAtipamezole is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM. 了解更多 -
Lanopepden
Catalog No. A21351 peptide deformylase inhibitorLanopepden (GSK 1322322) is a peptide deformylase inhibitor active against Staphylococcus aureus strains with MICs of 1 and 1 mg/L for ATCC 29213 and ATCC 25923 strain, respectively. 了解更多 -
Rasagiline 13C3 mesylate racemic
Catalog No. A21350 Monoamine oxidase inhibitorRasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. 了解更多 -
DHBS
Catalog No. A21334 DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems. 了解更多 -
Tonapofylline
Catalog No. A21328 adenosine A1 receptor antagonistTonapofylline (BG 9928) is an orally active and selective adenosine A1 receptor antagonist with a Ki of 7.4 nM for human adenosine A1 receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold selectivity versus human adenosine A2B receptor and is used in development for the treatment of heart failure. 了解更多 -
Nitro blue tetrazolium chloride
Catalog No. A21323 Dehydrogenases substrateNitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures. 了解更多 -
Dagrocorat
Catalog No. A21312 glucocorticoid receptor agonistDagrocorat (PF-00251802) is a novel and dissociated glucocorticoid receptor agonist. 了解更多 -
Potassium oxonate
Catalog No. A21302 uricase inhibitorPotassium oxonate is an inhibitor of uricase, inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro. 了解更多 -
Fedovapagon
Catalog No. A21286 V2R agonistFedovapagon is a selective vasopressin V2 receptor (V2R) agonist with an EC50 of 24 nM, which is being developed for the treatment of nocturia. 了解更多 -
Lazabemide
Catalog No. A21270 MAO-B inhibitorLazabemide(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). 了解更多 -
Fadrozole hydrochloride
Catalog No. A21258 Aromatase inhibitorFadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. 了解更多 -
Guadecitabine sodium
Catalog No. A21257 antineoplastic activityGuadecitabine, aslo known as SGI-110, is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. 了解更多 -
Letermovir
Catalog No. A21248 CMV inhibitorLetermovir is a novel inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. 了解更多 -
Soblidotin
Catalog No. A21227 tubulin polymerization inhibitorSoblidotin (Auristatin PE) is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization. 了解更多 -
Mavoglurant
Catalog No. A21223 mGlu5 receptor antagonistMavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5. 了解更多 -
L-371,257
Catalog No. A21219 oxytocin receptor antagonistL-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM). 了解更多 -
Rabacfosadine
Catalog No. A21217 cytotoxic agentRabacfosadine (GS-9219), a novel prodrug of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells. 了解更多
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