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产品 1001 到 1050 共 2783个

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  1. K-Ras G12C-IN-3

    Catalog No. A20931
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    K-ras G12C inhibitor
    K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. 了解更多
  2. DMAPT

    Catalog No. A20927
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    NF-κB inhibitor
    DMAPT (Dimethylamino Parthenolide), a water soluble analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect. 了解更多
  3. Diclofensine hydrochloride

    Catalog No. A20923
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    monoamine reuptake inhibitor
    Diclofensine hydrochloride (Ro-8-4650 hydrochloride) is a potent inhibitor of monoamine reuptake, blocking the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. 了解更多
  4. RS102895 hydrochloride

    Catalog No. A20918
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    CCR2 antagonist
    RS102895 hydrochloride is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1. 了解更多
  5. Dafadine-A

    Catalog No. A20914
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    DAF-9 cytochrome P450 inhibitor
    Dafadine-A, an analog of dafadine, is a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans; also inhibits the mammalian ortholog of DAF-9(CYP27A1). 了解更多
  6. DZ2002

    Catalog No. A20912
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    SAHH inhibitor
    DZ2002 is a potent and reversible S-Adenosyl-L-homocysteine Hydrolase(SAHH; AdoHcy Hydrolase) inhibitor with Ki of 17.9 nM. 了解更多
  7. FGH10019

    Catalog No. A20911
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    SREBP inhibitor
    FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM. 了解更多
  8. PP58

    Catalog No. A20906
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    PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR, FGFR and Src family activities with nanomolar IC50 values. 了解更多
  9. 10-Oxo Docetaxel

    Catalog No. A20899
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    10-Oxo Docetaxel (Docetaxel Impurity 1) is a novel taxoid having remarkable anti-tumor properties and a Docetaxel intermediate. 了解更多
  10. Ezutromid

    Catalog No. A20897
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    Small utrophin's translation modulator
    Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM . 了解更多
  11. Integrin Antagonists 27

    Catalog No. A20895
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    integrin αvβ3 antagonist
    Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. 了解更多
  12. HQ-415

    Catalog No. A20890
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    metal chelators
    HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting a EC50 for HQ-415 is 15 μM. 了解更多
  13. OICR-0547

    Catalog No. A20877
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    Wdr5-MLL interaction antagonist
    OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction, while OICR-0547 cannot bind to WDR5. 了解更多
  14. GLUFOSFAMIDE

    Catalog No. A20874
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    Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose. 了解更多
  15. IQ-R

    Catalog No. A20872
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    hypoxia-sensitive fluorescent probe
    IQ-R is a novel hypoxia-sensitive fluorescent probe, consisting of an indolequinone unit and a rhodol fluorophore. 了解更多
  16. RO8994

    Catalog No. A20865
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    MDM2 inhibitor
    RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays). 了解更多
  17. Azilsartan medoxomil monopotassium

    Catalog No. A20860
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    angiotensin II receptor type 1 antagonist
    Azilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. 了解更多
  18. Cefiderocol

    Catalog No. A20859
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    Cefiderocol (S-649266) is a novel siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less. 了解更多
  19. Centrinone

    Catalog No. A20858
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    PLK4 inhibitor
    Centrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM. 了解更多
  20. Centrinone-B

    Catalog No. A20855
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    PLK4 inhibitor
    Centrinone-B (LCR-323) is a potent and highly selective PLK4 inhibitor, with a Ki of 0.59 nM. 了解更多
  21. SIBA

    Catalog No. A20852
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    SIBA selectively inhibits spermine synthase, IC50=8 uM. 了解更多
  22. AS194949

    Catalog No. A20847
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    SHIP-2 inhibitor
    AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5?? phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes. 了解更多
  23. APNEA

    Catalog No. A20845
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    A3 adenosine receptor agonist
    APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent, non-selective A3 adenosine receptor agonist. 了解更多
  24. SYM2206

    Catalog No. A20843
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    AMPA receptor antagonist
    SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. 了解更多
  25. BAMB-4

    Catalog No. A20842
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    ITPKA inhibitor
    BAMB-4(ITPKA-IN-C14) is a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A((ITPKA) with IC50 of 37 μM in ADP-Glo Assay. 了解更多
  26. SN 2

    Catalog No. A20839
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    TRPML3 ion channel activator
    SN 2 is a novel and potent activator of TRPML3 ion channel with EC50 of 1.8??0.13 μM. 了解更多
  27. JD-5037

    Catalog No. A20837
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    CB1R antagonist
    JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM. 了解更多
  28. Talaporfin sodium

    Catalog No. A18239
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    photosensitizer
    Talaporfin (ME2906; NPe6) is a photosensitizer used in photodynamic therapy (PDT). 了解更多
  29. Temoporfin

    Catalog No. A18066
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    Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. Target: Others Temoporfin used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. Patients can remain photosensitive for several weeks after treatment. 了解更多
  30. Gadobutrol

    Catalog No. A18062
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    paramagnetic contrast agent
    Gadobutrol (Gd-DO3A-butrol; ZK 135079) is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). 了解更多
  31. Teriflunomide

    Catalog No. A18052
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    Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation. 了解更多
  32. Tenofovir alafenamide hemifumarate

    Catalog No. A18050
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  33. Tenofovir alafenamide fumarate

    Catalog No. A18049
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  34. Amifampridine

    Catalog No. A18048
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    Amifampridine (3,4-Diaminopyridine) is a drug, predominantly in the treatment of a number of rare muscle diseases. 了解更多
  35. Tenofovir hydrate

    Catalog No. A18042
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    nucleotide reverse transcriptase inhibitor
    Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多
  36. Tenofovir Disoproxil

    Catalog No. A18041
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    nucleotide reverse transcriptase inhibitor
    Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多
  37. Zoledronic acid monohydrate

    Catalog No. A18040
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    Zoledronic acid monohydrate is a third-generation, nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption, and also has antitumor activity. 了解更多
  38. Tacrolimus monohydrate

    Catalog No. A18039
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    immunosuppressant
    Tacrolimus monohydrate (FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate) is a macrocyclic lactone with potent immunosuppressive properties, an immunosuppressant. 了解更多
  39. Finafloxacin

    Catalog No. A18034
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    Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. 了解更多
  40. Cobimetinib hemifumarate

    Catalog No. A18033
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    MEK1 inhibitor
    Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM. 了解更多
  41. Efonidipine hydrochloride monoethanolate

    Catalog No. A18030
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    dual T-type and L-type calcium channel blocker
    Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). 了解更多
  42. Tafenoquine Succinate

    Catalog No. A18024
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    anti-malarial prophylactic agent
    Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent. 了解更多
  43. Hydrocortisone buteprate

    Catalog No. A18019
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    Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. 了解更多
  44. Pirmenol hydrochloride

    Catalog No. A18009
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    Pirmenol hydrochloride inhibits IK.ACh by blocking muscarinic receptors. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 μM. 了解更多
  45. Isocarboxazid

    Catalog No. A17887
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    monoamine oxidase inhibitor
    Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. 了解更多
  46. 2'-Deoxyguanosine

    Catalog No. A17864
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    2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. 了解更多
  47. Diclofenac

    Catalog No. A17814
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    COX inhibitor
    Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. 了解更多
  48. Alimemazine hemitartrate

    Catalog No. A17754
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    antipruritic agent
    Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. 了解更多
  49. Methyl linolenate

    Catalog No. A17731
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    Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. The IC50 is 60 uM. 了解更多
  50. Cytarabine hydrochloride

    Catalog No. A17692
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    nucleoside analog
    Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. 了解更多

产品 1001 到 1050 共 2783个

每页
页面:
  1. 19
  2. 20
  3. 21
  4. 22
  5. 23

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