Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ?300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM).
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