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产品 1201 到 1250 共 2783个

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  1. 5-Aminosalicylic Acid

    Catalog No. A10570
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    PPARγ agonist
    5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 了解更多
  2. 6-Thioguanine

    Catalog No. A10929
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    6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, 了解更多
  3. Norepinephrine

    Catalog No. A11306
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    β1-selective adrenergic receptor agonist
    Norepinephrine (Levarterenol; L-Noradrenaline) is a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM. 了解更多
  4. Radezolid

    Catalog No. A11550
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    Radezolid is a novel oxazolidinone antibiotic agent. 了解更多
  5. Aspirin

    Catalog No. A11797
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    COX-1/COX-2 inhibitor
    Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL. 了解更多
  6. Cisatracurium besylate

    Catalog No. A11834
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    neuromuscular blocking agent
    Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. 了解更多
  7. Daminozide

    Catalog No. A12916
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    plant growth regulator
    Daminozide(DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. 了解更多
  8. Noscapine

    Catalog No. A13910
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    Noscapine is an orally administrable drug used worldwide for cough suppression, primarily mediated by its ??-receptor agonist activity, and possess anticancer activity. 了解更多
  9. Pyrazinamide

    Catalog No. A10761
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    Pyrazinamide is an antimycobacterial compound that inhibits the growth of the human M. tuberculosis H37Rv strain. 了解更多
  10. ARV-771

    Catalog No. A13255
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    BET degrader
    ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively. 了解更多
  11. C 87

    Catalog No. A12313
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    TNFα inhibitor
    C87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM. 了解更多
  12. ABT-639

    Catalog No. A12330
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    T-type Ca2+ channel blocker
    ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. 了解更多
  13. TES-1025

    Catalog No. A13284
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    ACMSD inhibitor
    TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13??3 nM. 了解更多
  14. H100

    Catalog No. A12335
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    Cl- transport inhibitor
    H100 is a Cl- transport inhibitor, with partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger, but no effect against KCl cotransporter, in human erythrocytes. 了解更多
  15. Emixustat

    Catalog No. A12336
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    inhibitor of the visual cycle isomerase
    Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro. 了解更多
  16. Tecadenoson

    Catalog No. A13302
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    A1 adenosine receptor agonist
    Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist. 了解更多
  17. MIV-150

    Catalog No. A12060
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    NNRT inhibitor
    MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN. 了解更多
  18. Pomalidomide-PEG4-Ph-NH2

    Catalog No. A12066
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    E3 ligase ligand-linker conjugate
    Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. 了解更多
  19. Voxilaprevir

    Catalog No. A12067
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    HCV NS 3/4A protease inhibitor
    Voxilaprevir (GS-9857) is a fluorinated macrocyclic hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor with potent in vitro antiviral activity against genotypes 1-6 HCV and broad coverage of NS3/4A protease polymorphisms. GS-9857 improves coverage against commonly encountered NS3 resistance-associated variants (RAVs). 了解更多
  20. OPC-28326

    Catalog No. A12762
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    α2-adrenergic receptor angatonist
    OPC-28326 is a selective peripheral vasodilator and an angatonist of α2-adrenergic receptor, with Ki of 2040, 285, and 55?nM for α2A-, α2B- and α2C-adrenoceptors, respectively. 了解更多
  21. Cambinol

    Catalog No. A12381
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    SIRT1 and SIRT2 inhibitor
    Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 and 59 μM, respectively. 了解更多
  22. JNJ-17203212

    Catalog No. A12766
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    TRPV1 antagonist
    NJ-17203212 is a novel and selective TRPV1 antagonist, with IC50 of 65 nM and 102 nM for human TRPV1 and rat TRPV1. 了解更多
  23. RS-246204

    Catalog No. A13316
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    RS-246204 is a R-spondin-1 substitute compound that is able initiate small intestinal organoids without the use of the R-spondin-1 protein. 了解更多
  24. Uridine triphosphate

    Catalog No. A13317
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    nucleotide
    Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states. 了解更多
  25. Poloxime

    Catalog No. A12145
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    PLK1 inhibitor
    Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity. 了解更多
  26. PD-1-IN-18

    Catalog No. A12148
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    PD1 signaling pathway inhibitor
    PD-1-IN-18 is a PD1 signaling pathway inhibitor, which acts as an immunomodulator. 了解更多
  27. Remetinostat

    Catalog No. A12149
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    HDAC inhibitor
    Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma. 了解更多
  28. UK-157147

    Catalog No. A12455
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    substrate for UDP-glucuronosyltransferases (UGT1A1)
    UK-157147 is a substrate for UDP-glucuronosyltransferases (UGT1A1) with a Km value of 105 μM. 了解更多
  29. ST3932

    Catalog No. A12880
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    Adenosine A2A receptor antagonist
    ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. 了解更多
  30. Pico145

    Catalog No. A13344
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    TRPC1/4/5 channels inhibitor
    Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8. 了解更多
  31. PD-1-IN-17

    Catalog No. A12157
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    programmed cell death-1 (PD-1) inhibitor
    PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM. 了解更多
  32. Mepixanox

    Catalog No. A12458
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    analeptic drug used in respiratory and cardiorespiratory insufficiency
    Mepixanox (Pimexone) is an analeptic drug used in respiratory and cardiorespiratory insufficiency. 了解更多
  33. Polyoxyethylene stearate

    Catalog No. A12460
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    non-ionic emulsifying agent
    Polyoxyethylene stearate (POES) is a non-ionic emulsifying agent. 了解更多
  34. IX 207-887

    Catalog No. A13349
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    novel antiarthritic agent
    IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1). 了解更多
  35. Nafamostat

    Catalog No. A20827
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    serine protease inhibitor
    Nafamostat is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. 了解更多
  36. Nafamostat hydrochloride

    Catalog No. A20828
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    serine protease inhibitor
    Nafamostat hydrochloride is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. 了解更多
  37. Sophoradin

    Catalog No. A20833
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    Sophoradin is an isoprenyl chalconoid, a type of polyphenolic compound, found in Sophora tonkinensis, an herb used in traditional Chinese medicine. 了解更多
  38. Ebselen

    Catalog No. A20834
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    HIV-1 capsid CTD dimerization inhibitor
    Ebselen (SPI-1005) is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and inhibit inositol monophosphatase (IMPase). Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen inhibits QSOX1 enzymatic activity and has anticancer activity . 了解更多
  39. TRPC6-IN-1

    Catalog No. A12309
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    TRPC6 inhibitor
    TRPC6-IN-1 is a Transient Receptor Potential Canonical 6 Channel (TRPC6) inhibitor, with an EC50 of 4.66 μM. 了解更多
  40. Aligeron

    Catalog No. A13241
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    prostaglandin (PG) antagonist
    Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties. 了解更多
  41. Salicylamide

    Catalog No. A18252
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    Salicylamide is a non-steroidal anti-inflammatory agent with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. 了解更多
  42. MAC glucuronide phenol-linked SN-38

    Catalog No. A18403
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    DNA topoisomerase I inhibitor
    MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively. 了解更多
  43. Bax-activator-106

    Catalog No. A18406
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    Bax agonist
    Bax-activator-106 is a specific Bax agonist. It acts by promoting Bax-dependent but not Bak-dependent apoptosis. 了解更多
  44. 6-O-2-Propyn-1-yl-D-galactose

    Catalog No. A18439
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    6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic drugs and applications in antibody-drug conjugation. 了解更多
  45. SKF-34288 hydrochloride

    Catalog No. A18451
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    PEPCK inhibitor
    SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor. SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway. 了解更多
  46. CCR4 antagonist 2

    Catalog No. A18471
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    CCR4 拮抗剂
    CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. 了解更多
  47. Alpha-Naphthoflavone

    Catalog No. A18474
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    aromatase inhibitor
    Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. 了解更多
  48. MC-Val-Cit-PAB-duocarmycin

    Catalog No. A18496
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    MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. 了解更多
  49. FLT3-IN-4

    Catalog No. A18509
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    FLT3 inhibitor
    FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia. 了解更多
  50. Reactive Blue 4

    Catalog No. A18510
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    Reactive Blue 4 is an anthraquinone dye, as a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media. Reactive Blue 4 is phytotoxic, cytotoxic and genotoxic. Reactive Blue 4 . 了解更多

产品 1201 到 1250 共 2783个

每页
页面:
  1. 23
  2. 24
  3. 25
  4. 26
  5. 27

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