Cell Metabolism
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Hydroxyflutamide (Hydroxyniphtholide)
Catalog No. A11865 Hydroxyflutamide (Hydroxyniphtholide)是一种氟他胺的代谢产物,被发现可抑制雌二醇诱导的MCF-7乳腺癌细胞增殖。 了解更多 -
PF 4981517
Catalog No. A12544 CYP3A4 抑制剂PF 4981517是一种有效且选择性的CYP3A4抑制剂(CYP3A4,CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM)。 了解更多 -
Ozagrel(OKY-046)
Catalog No. A10688 -
3-Cyano-7-ethoxycoumarin
Catalog No. A13365 Fluorescent P450 substrate3-Cyano-7-ethoxycoumarin是适合连续测定细胞色素P450混合功能单加氧酶的荧光底物。它是用于微粒体脱烷基酶研究的荧光探针。 了解更多 -
Mephenytoin
Catalog No. A13366 -
Methoxyresorufin
Catalog No. A13367 -
TAK-700 Salt (Orteronel Salt)
Catalog No. A13515 CYP17A1/androgen synthesis 抑制剂TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸,肾上腺和前列腺肿瘤组织中表达的酶CYP17A。 了解更多 -
Choline Fenofibrate
Catalog No. A15044 -
Azathramycin
Catalog No. A15010 -
Benzbromarone
Catalog No. A16201 -
Clarithromycin
Catalog No. A10225 cytochrome P4503A4 抑制剂Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。 了解更多 -
Haloperidol (Haldol)
Catalog No. A10446 -
Talarozole R enantiomer
Catalog No. A13113 Cytochrome P450 抑制剂Talarozole R enantiomer 通过阻断细胞色素P450酶同工酶CYP26(一种视黄酸羟化酶)来抑制视黄酸的代谢。 了解更多 -
Efavirenz
Catalog No. A15826 -
Sulfaphenazole
Catalog No. A17283 CYP2C9 inhibitorSulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. 了解更多 -
CYP17-IN-1
Catalog No. A12622 CYP17 inhibitorCYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多 -
Liarozole dihydrochloride
Catalog No. A21853 CYP450 dependent inhibitorLiarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). 了解更多 -
Seviteronel
Catalog No. A20996 CYP17 lyase inhibitorSeviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. 了解更多