Cell Metabolism

产品 601 到 623 共 623个

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  1. Hydroxyflutamide (Hydroxyniphtholide)

    Catalog No. A11865
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    Hydroxyflutamide (Hydroxyniphtholide)是一种氟他胺的代谢产物,被发现可抑制雌二醇诱导的MCF-7乳腺癌细胞增殖。 了解更多
  2. PF 4981517

    Catalog No. A12544
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    CYP3A4 抑制剂
    PF 4981517是一种有效且选择性的CYP3A4抑制剂(CYP3A4,CYP3A5和CYP3A7的IC50值分别为0.03、17和70 μM)。 了解更多
  3. Ozagrel(OKY-046)

    Catalog No. A10688
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    TXAS 抑制剂
    Ozagrel(OKY-046)是一种有效的选择性血栓烷A2合成酶抑制剂,IC50为4 nM。 了解更多
  4. ABT

    Catalog No. A13361
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    Cytochrome P450 抑制剂
    ABT (1-Aminobenzotriazole)是(CYP)细胞色素P-450和氯过氧化物酶的自杀底物。 了解更多
  5. 3-Cyano-7-ethoxycoumarin

    Catalog No. A13365
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    Fluorescent P450 substrate
    3-Cyano-7-ethoxycoumarin是适合连续测定细胞色素P450混合功能单加氧酶的荧光底物。它是用于微粒体脱烷基酶研究的荧光探针。 了解更多
  6. Mephenytoin

    Catalog No. A13366
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    CYP2C19 and CYP2B6 substrate
    Mephenytoin是CYP2C19的底物。抗惊厥药。 了解更多
  7. Methoxyresorufin

    Catalog No. A13367
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    cytochrome P450 substrate
    Methoxyresorufin是细胞色素P450连接的酶的荧光底物。 了解更多
  8. TAK-700 Salt (Orteronel Salt)

    Catalog No. A13515
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    CYP17A1/androgen synthesis 抑制剂
    TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸,肾上腺和前列腺肿瘤组织中表达的酶CYP17A。 了解更多
  9. Luliconazole

    Catalog No. A11481
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    Luliconazole是一种唑类抗真菌药物,适用于指型足癣的局部治疗。 了解更多
  10. Choline Fenofibrate

    Catalog No. A15044
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    CYP2C19/CYP2B6 抑制剂
    Choline Fenofibrate (ABT-335)是非诺贝特酸的胆碱盐,与瑞舒伐他汀联合用于治疗血脂异常。 了解更多
  11. Azathramycin

    Catalog No. A15010
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    CYP3A4 抑制剂
    Azathramycin是一种抗生素。阿奇霉素与细菌核糖体的50S亚基结合,从而抑制mRNA的翻译。 了解更多
  12. Benzbromarone

    Catalog No. A16201
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    CYP2C9 抑制剂
    Benzbromarone是一种CYP2C9抑制剂,它以19.3 nM的Ki值与CYP2C9结合。 了解更多
  13. Chlorzoxazone

    Catalog No. A16449
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    Chlorzoxazone是一种放松肌肉的药物,也是人类肝脏细胞色素P-450IIE1的探针。 了解更多
  14. Clarithromycin

    Catalog No. A10225
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    cytochrome P4503A4 抑制剂
    Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。 了解更多
  15. Haloperidol (Haldol)

    Catalog No. A10446
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    CYP2D6 抑制剂
    Haloperidol (Haldol)是一种抗精神病药和丁二酮。 了解更多
  16. Talarozole R enantiomer

    Catalog No. A13113
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    Cytochrome P450 抑制剂
    Talarozole R enantiomer 通过阻断细胞色素P450酶同工酶CYP26(一种视黄酸羟化酶)来抑制视黄酸的代谢。 了解更多
  17. Efavirenz

    Catalog No. A15826
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    cytochrome P450 抑制剂
    Efavirenz是一种非核苷类逆转录酶抑制剂(NNRTI)。 了解更多
  18. Sulfaphenazole

    Catalog No. A17283
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    CYP2C9 inhibitor
    Sulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. 了解更多
  19. CYP17-IN-1

    Catalog No. A12622
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    CYP17 inhibitor
    CYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多
  20. Bergaptol

    Catalog No. A12303
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    CYP3A4 enzyme inhibitor
    Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties. 了解更多
  21. Liarozole dihydrochloride

    Catalog No. A21853
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    CYP450 dependent inhibitor
    Liarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). 了解更多
  22. Seviteronel

    Catalog No. A20996
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    CYP17 lyase inhibitor
    Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. 了解更多
  23. Veledimex

    Catalog No. A21011
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    CYP3A4/5 inhibitor and substrate
    Veledimex is an oral activator ligand for a proprietary gene therapy promoter system, and a moderate inhibitor of and substrate for CYP3A4/5. 了解更多

产品 601 到 623 共 623个

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  3. 11
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