Product Data Sheet
SB-399885 hydrochloride
Catalog No. A14102
SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively).
| Catalog Num | A14102 |
|---|---|
| M. Wt | 482.8 |
| Formula | C18H22Cl3N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 402713-81-9 |
| Synonyms | SB399885, SB-399885 |
| SMILES | COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2OC)Cl)Cl)N3CCNCC3.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| Discription | SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively). |
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