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JAK / Stat

JAK / Stat

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FLLL32

Catalog No. A15911
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JAK2 抑制剂

FLLL32是一种有效的JAK2/STAT3双重抑制剂，IC50 <5 uM。了解更多

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Cucurbitacin I

Catalog No. A15363
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JAK2/STAT3 抑制剂

Cucurbitacin I（Cucumis sativus L.）可以抑制v-Src转化的NIH 3T3细胞中的磷酸酪氨酸Stat3（信号转导和转录激活因子3）水平。了解更多

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SD 1008

Catalog No. A15364
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JAK2/STAT3 抑制剂

SD 1008是JAK2/STAT3信号通路抑制剂，可额外抑制Src。注意到SD 1008可诱导表达组成性活性酪氨酸磷酸化STAT3的细胞系凋亡。了解更多

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C188-9

Catalog No. A16804
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STAT3 抑制剂

C188-9是一种有效的STAT3抑制剂，它以高亲和力（KD = 4.7±0.4 nM）与STAT3结合。C188-9在小鼠中具有良好的耐受性，显示出良好的口服生物利用度，并且集中在肿瘤中。了解更多

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STAT3-IN-3

Catalog No. A18479
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STAT3 inhibitor

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3). 了解更多

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HJC0152

Catalog No. A16806
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STAT3 抑制剂

HJC0152是一种STAT3抑制剂，具有显着改善的水溶性。了解更多

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STAT3-IN-1

Catalog No. A12232
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STAT3 inhibitor

STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor apoptosis. 了解更多

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