COX

Catalog No.Inhibitor Name COXCOX-1COX-2Other
A10193Celecoxib
****
A10461Ibuprofen
*
*
A10474Indomethacin
**
*
A11918Rofecoxib
****
A10304Diclofenac Sodium
***
***
A11695Lornoxicam
****
****
A10623Naproxen Sodium
*
*
A13342Valdecoxib
****
A11693Tolfenamic Acid
***
A16399Amfenac Sodium Monohydrate
**
***
A11694Nimesulide
*
A12520Meclofenamate Sodium
****
***
A16428Carprofen
****
A10636Nepafenac
A10878Sulindac
A10565Meloxicam
A10820Aspirin
A11906Phenacetin
A10736Piroxicam
A10462Ibuprofen Lysine
A11641Pranoprofen
A10090Asaraldehyde
A11692Acemetacin
A13244Bromfenac Sodium

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

产品 51 到 60 共 60个

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  1. Metamizole sodium hydrate

    Catalog No. A18270
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    COX 抑制剂
    Dipyrone, also known as Anador and NSC-73205, is a nonsteroidal anti-inflammatory drug used to treat pain (postoperative, colic, cancer, and migraine). 了解更多
  2. Bromfenac sodium hydrate

    Catalog No. A18194
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    COX-2 抑制剂
    Bromfenac Sodium Sesquihydrate is a nonsteroidal anti-inflammatory drug (NSAID), which inhibits cyclooxygenase II (COX-2). 了解更多
  3. Deracoxib

    Catalog No. A18077
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    NSAID and COX-2 抑制剂
    Deracoxib is an NSAID and COX-2 inhibitor used to treat osteoarthritis. It induces cell cycle arrest and apoptosis in mammary tumor cells, decreases platelet aggregation, and lowers inflammatory responses. 了解更多
  4. Imrecoxib

    Catalog No. A18027
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    COX-2 抑制剂
    Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor with an IC50 value of 18 nM, it also inhibits COX1- activity with an IC50 value of 115 nM. Imrecoxib (BAP-909) has anti-inflammatory effect. 了解更多
  5. Naproxen

    Catalog No. A17550
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    COX 抑制剂
    Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. 了解更多
  6. Aceclofenac

    Catalog No. A17433
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    COX-2 抑制剂
    Aceclofenac is a cyclooxygenase-2 inhibitor used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. 了解更多
    • 最新产品

    Firocoxib

    Catalog No. A17245
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    COX-2 抑制剂
    Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class, currently approved for use in dogs and horses. 了解更多
  7. Ketorolac

    Catalog No. A17248
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    COX 抑制剂
    Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. 了解更多
  8. Timegadine

    Catalog No. A17108
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    COX and lipo-oxygenase 抑制剂
    Timegadine被发现是一种有效的竞争性环加氧酶(COX)和脂加氧酶抑制剂,IC50的范围从5 nM(洗兔血小板)到20μM(大鼠脑)。在马血小板匀浆的细胞溶质级分和洗涤过的兔血小板中,脂氧化酶的浓度为100μM和100μM。 了解更多
  9. Carprofen

    Catalog No. A16428
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    COX-2 抑制剂
    Carprofen通过抑制COX-2和其他炎症性前列腺素来减轻炎症,不干扰COX-1活性。 了解更多

产品 51 到 60 共 60个

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