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￥ 0.00 Neuronal Signaling
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Anisodamine
Catalog No. A18215 alpha-1 adrenergic receptors / mAChRs inhibitorAnisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多 -
Cimetropium Bromide
Catalog No. A18290 mAChR antagonistCimetropium Bromide (DA-3177) is a mAChR antagonist for long-term treatment of irritable bowel syndrome. 了解更多 -
Darenzepine
Catalog No. A12333 muscarinic receptor inhibitorDarenzepine is a muscarinic receptor inhibitor extracted from patent US 20170095465 A1. 了解更多 -
Tiotropium Bromide
Catalog No. A10934 muscarinic acetylcholine receptor (mAChR) antagonistTiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. 了解更多 -
Rapacuronium bromide
Catalog No. A21119 mAChR modulatorRapacuronium bromide is an allosteric modulator of muscarinic acetylcholine receptor (mAChR). 了解更多 -
mAChR-IN-1 hydrochloride
Catalog No. A21398 mAChR antagonistmAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM. 了解更多 -
mAChR-IN-1
Catalog No. A21518 mAChR antagonistmAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM. 了解更多 -
(Rac)-VU 6008667
Catalog No. A21939 mAChR M5 negative allosteric modulator(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration. 了解更多 -
Oxotremorine M iodide
Catalog No. A21977 mAChR agonistOxotremorine M iodide is a potent and non-selective muscarinic acetylcholine receptor (mAChR) agonist. 了解更多 -
PNU 282987
Catalog No. A11233 -
Ispronicline (TC-1734, AZD-3480)
Catalog No. A14183 nAChR 激动剂Ispronicline (TC-1734,AZD-3480)是神经元烟碱乙酰胆碱受体部分激动剂。Ispronicline是亚型选择性的，主要与a4b2亚型结合。它具有抗抑郁、益智和神经保护作用。 了解更多 -
Sofinicline (ABT-894, A-422894)
Catalog No. A13842 -
5-Iodo-A-85380 2HCl
Catalog No. A13639 -
A-582941
Catalog No. A13539 -
EVP-6124 (Encenicline)
Catalog No. A15086 nAChR 抑制剂EVP-6124 (Encenicline)是α7神经元烟碱乙酰胆碱受体（nAChRs）的新型部分激动剂；显示对α7nAChRs的选择性，并且不激活或抑制异聚体α4β2nAChRs。 了解更多 -
EVP-6124 hydrochloride
Catalog No. A15087 nAChR 抑制剂EVP-6124 hydrochloride是一种新型的α7神经元烟碱型乙酰胆碱受体（nAChRs）的部分激动剂。EVP-6124对α7nAChRs具有选择性，并且不激活或抑制异源α4β2nAChRs。 了解更多 -
GTS-21 (DMBX-A)
Catalog No. A15950 nAChR 激动剂GTS-21 dihydrochloride (DMBX-A)是一种选择性的α7烟碱乙酰胆碱受体激动剂，最近已被确定为一种有希望的炎症治疗方法。 了解更多 -
Benzethonium Chloride
Catalog No. A13653 nAChR 抑制剂Benzethonium Chloride是nAChRs的有效抑制剂，可抑制α4β2nAChRs和α7nAChRs，IC50分别为49 nM和122 nM。 了解更多 -
Mecamylamine Hydrochloride
Catalog No. A17884 nAChR antagonistMecamylamine hydrochloride is a nAChR antagonist previously used to treat hypertension. It displays a wide variety of activities, including reducing depression-like behaviors in subjects with Tourette's syndrome and improving rates of smoking cessation. 了解更多 -
(-)-(S)-B-973B
Catalog No. A18761 α7 nAChR modulator-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity. 了解更多 -
PNU-120596
Catalog No. A11203 -
Adiphenine HCl
Catalog No. A11716 -
Methyllycaconitine citrate
Catalog No. A12681 Methyllycaconitine citrate是含有α7的神经元烟碱受体（Ki = 1.4 nM）的有效拮抗剂。与浓度大于40 nM的α4β2和α6β2受体相互作用。 了解更多 -
Tropisetron HCL
Catalog No. A14375 5-HT3 receptor 拮抗剂Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂，对5-HT3受体的IC50为70.1±0.9 nM。 了解更多 -
Bephenium hydroxynaphthoate
Catalog No. A17391 B-type AChR activatorBephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis; B-type AChR activator. 了解更多 -
Varenicline Hydrochloride
Catalog No. A21539 α4β2 nAChR partial agonistVarenicline Hydrochloride (CP 526555 hydrochloride) is a high affinity, selective α4β2 nicotine acetylcholine receptor (nAChR) partial agonist and full α7 nAChR agonist. 了解更多 -
Tebanicline hydrochloride
Catalog No. A21918 nAChR modulatorTebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. 了解更多 -
A 438079 hydrochloride
Catalog No. A14983 P2X7 receptor 拮抗剂A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂（抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9）。 了解更多 -
JNJ-54175446
Catalog No. A18675 P2X7 receptor antagonistJNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. 了解更多 -
A 839977
Catalog No. A21178 -
CE-224535
Catalog No. A21183 -
GW791343 trihydrochloride
Catalog No. A21204 P2X7 allosteric modulatorGW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多 -
Minodronic acid
Catalog No. A21975 purinergic P2X2/3 receptors antagonistMinodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain. 了解更多 -
GW791343 HCl
Catalog No. A11107 -
Ticlopidine HCl
Catalog No. A11690 Ticlopidine是一种二磷酸腺苷（ADP）受体抑制剂。它通过阻断ADP受体来改变血小板膜的功能，从而抑制血小板聚集。这防止了糖蛋白IIb/IIIa的构象变化，从而使血小板与血纤蛋白原结合。 了解更多 -
NF 279
Catalog No. A11972 -
A-317491 sodium salt hydrate
Catalog No. A12412 P2X3 and P2X2/3 receptor 拮抗剂A-317491 sodium salt hydrate是一种非核苷酸的P2X3和P2X2/3受体拮抗剂，可抑制受体介导的钙通量。 了解更多 -
A-438079 HCl
Catalog No. A12597 P2X7 receptor 拮抗剂A-438079 HCl是一种竞争性P2X7受体拮抗剂（抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9）。在其他P2受体上没有活性（IC50 > 10 uM）。 了解更多 -
Cangrelor Tetrasodium
Catalog No. A17919 P2Y12 receptors inhibitorCangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion. 了解更多
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