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Teriflunomide

Teriflunomide

Name: Teriflunomide
SKU: A18052

目录号: A18052

Teriflunomide Chemical Structure

CAS NO. 163451-81-8

Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.

库存：现货

规格	价格	数量
50 mg	￥ 441.00
100 mg	￥ 763.00
500 mg	￥ 2,254.00

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生物活性

Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.

溶解度 *

In vitro	DMSO	28 mg/mL (103.62 mM)
	Water	Insoluble
	Ethanol	<1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.01 mL	185.04 mL	370.08 mL
0.5 mM	7.4 mL	37.01 mL	74.02 mL
1 mM	3.7 mL	18.5 mL	37.01 mL
5 mM	0.74 mL	3.7 mL	7.4 mL

*The above data is based on the productmolecular weight 270.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18052
M. Wt	270.21
Formula	C12H9F3N2O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	163451-81-8
Synonyms	A77 1726, A77-1726
SMILES	C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O.[(Z)]