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Vps34-IN-2是一种新颖，有效和选择性的Vps34抑制剂，在Vps34酶促测定和GFP-FYVE细胞测定中的IC50分别为2和82 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.85 mL | 124.25 mL | 248.5 mL |
| 0.5 mM | 4.97 mL | 24.85 mL | 49.7 mL |
| 1 mM | 2.49 mL | 12.43 mL | 24.85 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16933 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 402.41 |
| Formula | C18H25F3N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1523404-29-6 |
| SMILES | O=C1C=C(N2[C@H](C)COCC2)N=C3N(CC(C(C)C)=O)[C@H](C(F)(F)F)CCN31 |
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