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10-DEBC HCl是Akt/PKB的选择性抑制剂。它抑制IGF-1刺激的磷酸化和Akt的激活（在2.5μM时完全抑制），抑制mTOR，p70 S6激酶的下游激活。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.23 mL | 131.13 mL | 262.26 mL |
| 0.5 mM | 5.25 mL | 26.23 mL | 52.45 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.23 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.25 mL |
*The above data is based on the productmolecular weight 381.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13590 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 381.3 |
| Formula | C20H25ClN2OHCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 925681-41-0 |
| Synonyms | Akt Inhibitor X |
| SMILES | CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl |
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