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￥ 0.00 Epigenetics
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MS-275 (Entinostat)
Catalog No. A10611 HDAC 抑制剂MS-275 (Entinostat)是一种有效的HDAC抑制剂，对HDAC1和HDAC3的IC50分别为0.3和8uM。 了解更多 -
Trichostatin-A (TSA)
Catalog No. A10947 HDAC 抑制剂Trichostatin-A (TSA)是抑制HDAC 1、3、4、6和10，IC50值约为20 nM。 了解更多 -
Belinostat (PXD101)
Catalog No. A10122 HDAC 抑制剂Belinostat（PXD101）是一种HDAC抑制剂，可抑制HeLa细胞提取物中的HDAC活性，IC50为27 nM。 了解更多 -
LBH589 (Panobinostat)
Catalog No. A10518 HDAC 抑制剂LBH589是异羟肟酸，用作非选择性HDAC抑制剂，HDAC1的IC5o为0.23 nM。 了解更多 -
CUDC-101
Catalog No. A10246 -
MGCD0103 (Mocetinostat)
Catalog No. A10586 HDAC 抑制剂MGCD0103 (Mocetinostat)是一种苯甲酰胺组蛋白脱乙酰基酶抑制剂，主要抑制组蛋白脱乙酰基酶1（HDAC1），但也抑制HDAC2，HDAC3和HDAC11。 了解更多 -
Vorinostat (SAHA)
Catalog No. A10979 HDAC 抑制剂Vorinostat (SAHA)是HDAC的抑制剂，抑制脱乙酰和导致双方超乙酰化组蛋白和转录因子的积累。 了解更多 -
ITF2357 (Givinostat)
Catalog No. A10488 -
Droxinostat
Catalog No. A10337 HDAC 抑制剂Droxinostat是HDAC3，HDAC6和HDAC8的选择性抑制剂，显示出可比较的HDAC6和HDAC8抑制作用，IC50分别为2.47和1.46μmol/ L。 了解更多 -
AR-42 (HDAC-42)
Catalog No. A11037 HDAC 抑制剂AR-42 (HDAC-42)是一种新型的HDAC抑制剂，通过下调本构激活的Kit表现出对恶性肥大细胞系的生物学活性。 了解更多 -
PCI-24781 (Abexinostat)
Catalog No. A10700 -
Tubastatin A HCl
Catalog No. A11042 HDAC6 抑制剂Tubastatin A HCl是一种有效的选择性HDAC6抑制剂，在无细胞试验中IC50为15 nM。它对除HDAC8（57倍）以外的所有其他同工酶（1000倍）具有选择性。 了解更多 -
SB939 ( Pracinostat )
Catalog No. A10830 HDAC 抑制剂SB939 (Pracinostat)是HDAC的口服抑制剂，对I，II和IV类HDAC具有选择性，在体外HDAC1活性测定中显示IC50值为77 nM。 了解更多 -
JNJ-26481585 (Quisinostat)
Catalog No. A10492 HDAC 抑制剂JNJ-26481585 (Quisinostat)是一种pan-HDAC抑制剂，对HDAC1具有显著的效力(IC(50)，0.16 nmol/L)。 了解更多 -
Pyroxamide (NSC 696085)
Catalog No. A10764 HDAC 抑制剂Pyroxamide (NSC 696085)是亲和纯化的HDAC1的有效抑制剂，可导致乙酰化核心组蛋白在用该试剂培养的MEL细胞中积累。 了解更多 -
PCI-34051
Catalog No. A11152 -
CUDC-907 (Fimepinostat)
Catalog No. A11153 PI3K/HDAC 抑制剂CUDC-907 (Fimepinostat)是针对PI3K和HDAC的单一小分子抑制剂，作用于PI3Kα和HDAC1/2/3/10，IC50分别为19 nM和1.7 nM/5 nM/1.8 nM/2.8 nM。 了解更多 -
Parthenolide ((-)-Parthenolide)
Catalog No. A10698 Parthenolide ((-)-Parthenolide), Nuclear Factor-κB抑制剂，可特异性地耗尽HDAC1蛋白，而不影响其他I/II类 HDACs。促进MDM2的泛素化并激活p53的细胞功能。 了解更多 -
LAQ824 (NVP-LAQ824, Dacinostat)
Catalog No. A10516 HDAC 抑制剂LAQ824 (NVP-LAQ824)是一种有效的新型组蛋白去乙酰化酶抑制剂，具有显著的抗多发性骨髓瘤活性。 了解更多 -
ACY-1215 (Rocilinostat)
Catalog No. A11940 HDAC6 抑制剂ACY-1215 (Rocilinostat)是一种选择性HDAC6抑制剂，从而通过Hsp90的超乙酰化作用破坏Hsp90蛋白伴侣系统，并防止随后的总蛋白降解。 了解更多 -
CI994 (Tacedinaline)
Catalog No. A11964 -
Romidepsin (FK228 ,Depsipeptide)
Catalog No. A11920 HDAC 抑制剂Romidepsin (FK228,Depsipeptide)抑制HDAC1和HDAC2，IC50分别为1.6 nM和3.9 nM，但相对较弱地分别抑制HDAC4和HDAC6，IC50值为25 nM和79 nM。 了解更多 -
RGFP966
Catalog No. A13218 -
Resminostat
Catalog No. A12556 HDAC 抑制剂Resminostat，也称为RAS2410，是一种有效的I和II类组蛋白脱乙酰基酶（HDAC）抑制剂。它结合并抑制HDAC，从而导致高度乙酰化的组蛋白的积累。选择性的抑制HDAC1/3/6，IC50为42.5 nM/50.1 nM/71.8 nM，作用于HDAC8效果弱，IC50为877 nM。 了解更多 -
RG2833 (RGFP109)
Catalog No. A13139 -
BRD73954
Catalog No. A15489 -
Resminostat hydrochloride
Catalog No. A15220 HDAC 抑制剂Resminostat hydrochloride是HDAC1/3/6的有效抑制剂（IC50 = 43-72 nM）；对HDAC8的效力较低，IC50为877 nM。 了解更多 -
KD 5170
Catalog No. A15354 -
Citarinostat (ACY-241)
Catalog No. A12758 HDAC6 抑制剂ACY-241是HDAC6的新型，选择性和口服抑制剂。对HDAC6和HDAC3的IC50分别为2.6 nM和46 nM。 了解更多 -
CRA-026440
Catalog No. A12179 -
Valproic acid sodium salt
Catalog No. A10855 HDAC inhibitorValproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. 了解更多 -
JAK/HDAC-IN-1
Catalog No. A13362 JAK2/HDAC dual inhibitorJAK/HDAC-IN-1 is a potent JAK2/HDAC dual inhibitor, exhibits antiproliferative and proapoptotic activities in several hematological cell lines. 了解更多 -
Sodium phenylbutyrate
Catalog No. A16714 HDAC/ER stress inhibitorSodium phenylbutyrate is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research. 了解更多 -
Tubastatin A
Catalog No. A16770 HDAC6 inhibitorTubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). 了解更多 -
Givinostat
Catalog No. A21126 HDAC inhibitorGivinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. 了解更多 -
Givinostat hydrochloride
Catalog No. A21487 HDAC inhibitorGivinostat hydrochloride (ITF-2357 hydrochloride) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. 了解更多 -
Nanatinostat
Catalog No. A21625 HDAC inhibitorNanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM. 了解更多 -
Belinostat
Catalog No. A21772 HDAC inhibitorBelinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC50 of 27 nM in HeLa cell extracts. 了解更多 -
HDAC-IN-5
Catalog No. A20972 -
Domatinostat tosylate
Catalog No. A20986 HDAC1 inhibitorDomatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). 了解更多
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