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Mps1-IN-1是一种高效的选择性Mpls抑制剂，IC50为367 nM。相对于352个成员激酶组，选择性> 1000倍，主要是Alk和Ltk。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.67 mL | 93.34 mL | 186.69 mL |
| 0.5 mM | 3.73 mL | 18.67 mL | 37.34 mL |
| 1 mM | 1.87 mL | 9.33 mL | 18.67 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.73 mL |
*The above data is based on the productmolecular weight 535.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11218 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 535.66 |
| Formula | C28H33N5O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1125593-20-5 |
| SMILES | OC1CCN(C2=CC(OC)=C(NC3=NC4=C(C=CN4)C(NC5=C(S(=O)(C(C)C)=O)C=CC=C5)=C3)C=C2)CC1 |
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