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4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.33 mL | 181.65 mL | 363.29 mL |
| 0.5 mM | 7.27 mL | 36.33 mL | 72.66 mL |
| 1 mM | 3.63 mL | 18.16 mL | 36.33 mL |
| 5 mM | 0.73 mL | 3.63 mL | 7.27 mL |
*The above data is based on the productmolecular weight 275.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18513 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 275.26 |
| Formula | C12H13N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 306305-07-7 |
| Synonyms | 4'-E-dA, 4-E-dA |
| SMILES | OC[C@]1(C#C)[C@H](C[C@H](N2C=NC3=C(N=CN=C32)N)O1)O |
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