微信关注
Total item
Cart Subtotal
￥ 0.00 5-HT Receptors
-
Tandospirone
Catalog No. A13293 5-HT Receptor 拮抗剂Tandospirone是5HT1A受体的部分激动剂。它以剂量依赖性方式显着降低氟哌啶醇诱导的运动迟缓。 了解更多 -
SB-742457
Catalog No. A14092 -
SB 399885 HCl
Catalog No. A14102 5-HT6 拮抗剂SB 399885 hydrochloride是一种有效的，脑渗透剂和口服活性的SR-6拮抗剂。它对SR-6的选择性比其他血清素受体高200倍（对于人类重组，天然大鼠和天然人类SR-6受体，pKi值分别为9.11、8.81和9.02）。 了解更多 -
Cyclobenzaprine HCl
Catalog No. A14255 -
Levomilnacipran HCl
Catalog No. A14391 -
Tropisetron HCL
Catalog No. A14375 5-HT3 receptor 拮抗剂Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂，对5-HT3受体的IC50为70.1±0.9 nM。 了解更多 -
Flibanserin
Catalog No. A13860 Flibanserin是一种正在研究中用于预防女性HSDD的新药。是一种新型的多功能性五羟色胺受体激动剂和拮抗剂 (MSAA)。 了解更多 -
Edivoxetine HCl
Catalog No. A13865 -
S 32212 HCl
Catalog No. A13501 -
Norfluoxetine
Catalog No. A13458 serotonin uptake 抑制剂Norfluoxetine是抗抑郁药氟西汀的活性代谢物，抑制5-羟色胺的摄取，pKi值为7.35.1氟西汀的S-对映体的5-羟色胺再摄取阻断能力是R-对映体的20倍（pKis分别为7.86和6.51）。 了解更多 -
NAN-190 hydrobromide
Catalog No. A13417 5-HT1A receptor 拮抗剂NAN-190 hydrobromide是一种广泛用于科学研究的药物和研究化学品。以前认为它是一种选择性的5-HT1A受体拮抗剂，但后来的发现表明它也能有效地阻断α2肾上腺素能受体。 了解更多 -
Atomoxetine HCl
Catalog No. A13424 norepinephrine (NE) transporter 抑制剂Atomoxetine HCl是SLC6A2的一种竞争性特异性抑制剂，同时在大鼠下丘脑突触体中显示出微弱的ST和DAT抑制作用。 了解更多 -
Clozapine N-oxide
Catalog No. A15048 5-HT1C receptor 拮抗剂Clozapine N-oxide是氯氮平的主要代谢产物，在体外可降低SR-2A（5-HT2血清素受体）密度。 了解更多 -
Ziprasidone
Catalog No. A15286 5-HT/dopamine receptor 拮抗剂Ziprasidone是5-HT（5-羟色胺）和多巴胺受体拮抗剂的组合，具有抗精神病活性。 了解更多 -
Alosetron Hydrochloride
Catalog No. A14989 -
Asenapine HCl
Catalog No. A15002 adrenergic receptor/5-HT receptor 抑制剂Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。 了解更多 -
Desvenlafaxine succinate hydrate
Catalog No. A15491 serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂，Ki值分别为40.2 nM和558.4 nM 了解更多 -
Pardoprunox HCl (SLV-308)
Catalog No. A11538 Pardoprunox HCl (SLV-308)是一种抗帕金森病药物，是多巴胺受体D2、D3和5-HT1A激动剂，用于治疗帕金森病。 了解更多 -
Eptapirone
Catalog No. A15923 5HT(1A) receptor 激动剂Eptapirone是一种有效的，选择性的，高效的5-HT1A受体激动剂，具有显着的抗焦虑和抗抑郁潜力。 了解更多 -
Pimavanserin
Catalog No. A15884 Serotonin2A Receptor Inverse 激动剂Pimavanserin是一种有效的选择性5-羟色胺5-HT2A反向激动剂，pIC50为8.73，用于治疗与帕金森氏病有关的精神病。 了解更多 -
Cyproheptadine hydrochloride
Catalog No. A16169 -
Buspirone HCl
Catalog No. A15687 5HT(1A) receptor 激动剂Buspirone hydrochloride是一种具有5-D（2）多巴胺能作用的血清素能（5HT（1A）受体激动剂）抗焦虑药，用于焦虑症。 了解更多 -
Amitriptyline HCl
Catalog No. A16404 Amitriptyline HCl抑制5-羟色胺受体，去甲肾上腺素受体，5-HT4、5-HT2和sigma 1受体，IC50分别为3.45 nM，13.3 nM，7.31 nM，235 nM和287 nM。 了解更多 -
Azasetron HCl
Catalog No. A16417 5-HT3 receptor 拮抗剂Azasetron HCl是一种选择性的5-HT3受体拮抗剂，IC50为0.33 nM，用于治疗癌症化学疗法引起的恶心和呕吐。 了解更多 -
Eucalyptol
Catalog No. A15662 -
Temanogrel
Catalog No. A17094 5-HT(2A) receptor 激动剂Temanogrel，也称为APD791，是一种高度选择性的5-羟基色胺2A受体反向激动剂，正在开发中，用于治疗动脉血栓形成。 了解更多 -
LY 334370 hydrochloride
Catalog No. A17027 5-HT1F 激动剂LY 334370 hydrochloride是一种选择性的5-HT1F受体激动剂（Ki值为1.87、16.4，> 100 (IC50)）。CAS：199673-74-0（LY 334370盐酸盐）；182563-08-2（LY 334370游离碱） 了解更多 -
LY 344864 racemate
Catalog No. A17015 -
Volinanserin
Catalog No. A17115 -
Eptapirone (F-11440)
Catalog No. A18338 5-HT1A receptor agonistEptapirone is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (pKi, 7.50), and somewhat lower than that of flesinoxan (pKi, 8.91). In vivo, F 11440 was 4- to 20-fold more potent than flesinoxan, and 30- to 60-fold more potent than buspirone. 了解更多 -
Dolasetron
Catalog No. A17595 5-HT3 receptor antagonistDolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. 了解更多 -
Nefazodone hydrochloride
Catalog No. A17622 5-HT2 receptors inhibitorNefazodone HCl is an inhibitor of 5-HT2 receptors, SERT, NET, and hERG K+ channels used to treat mood disorders. It decreases immobility time in the forced swim test. 了解更多 -
Dolasetron Mesylate
Catalog No. A17729 5-HT3 receptor antagonistDolasetron mesylate is a selective 5-HT3 receptor antagonist. 了解更多 -
Alprenolol hydrochloride
Catalog No. A17781 5-HT1A receptor antagonistAlprenolol (hydrochloride) is a non-selective beta blocker as well as 5-HT1A receptor antagonist. 了解更多 -
Alosetron (Hydrochloride(1:X))
Catalog No. A11309 Serotonin 5HT3-receptor antagonistAlosetron Hydrochloride(1:X) (GR 68755 Hydrochloride(1:X)) is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome. 了解更多
FILTER BY:
购物选项
- 作用机制
-
- Inhibitor (抑制剂) (16)
- Agonist (激动剂) (39)
- Antagonist (拮抗剂) (72)
- Modulator (调节剂) (2)
ADOOQ 产品质量保证
We promise all products to perform as described.