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GPCR / G Protein

产品 201 到 229 共 229个

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  1. Senktide
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    Senktide

    Catalog No. A16945
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    NK3 receptor 激动剂
    Senktide是神经介素K3（NK3）受体的有效选择性激动剂（EC50 = 0.5-3 nM）。 了解更多
  2. Cenerimod
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    Cenerimod

    Catalog No. A20913
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    S1P1 agonist
    Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM. 了解更多
  3. FTY720 (S)-Phosphate
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    FTY720 (S)-Phosphate

    Catalog No. A21324
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    S1PR1 agonist
    FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury. 了解更多
  4. CYM 5442 HCl
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    CYM 5442 HCl

    Catalog No. A13637
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    EDG-1 (S1P1) 激动剂
    CYM 5442 HCl是一种有效的体外选择性EDG-1（S1P1）激动剂（EC50 = 1.35 nM）。 了解更多
  5. ASP1126
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    ASP1126

    Catalog No. A18432
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    S1P agonist
    ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist, with EC50 values of 7.12 nM, 517 nM for hS1P1 and hS1P3, respectively. 了解更多
  6. Cutamesine
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    Cutamesine

    Catalog No. A21152
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    sigma 1 receptor agonist
    Cutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(??1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4??1.9 nM); 100-fold less affinity for the sigma 2 receptor. 了解更多
  7. Ditolylguanidine
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    Ditolylguanidine

    Catalog No. A21268
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    Sigma receptor agonist
    Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (??1/??2 receptor). 了解更多
  8. Siramesine Hydrochloride
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    Siramesine Hydrochloride

    Catalog No. A12479
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    Sigma-2 receptor 激动剂
    Siramesine Hydrochloride是一种选择性sigma-2受体激动剂，已被证明可触发癌细胞的细胞死亡并在体内表现出强大的抗癌活性。 了解更多
  9. Siramesine
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    Siramesine

    Catalog No. A13036
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    Sigma-2 receptor 激动剂
    Siramesine是一种溶酶体去污剂，诱导细胞保护性自噬体积累。 了解更多
  10. SA-4503
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    SA-4503

    Catalog No. A12984
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    sigma 1 receptor(σ1R) 激动剂
    SA4503是选择性sigma 1受体（σ1R）激动剂；对（+）-[3H]喷他佐辛标记的sigma 1受体亚型具有高亲和力（IC50 = 17.4+/-1.9 nM）；对sigma 2受体的亲和力低100倍。 了解更多
  11. 4-IBP
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    4-IBP

    Catalog No. A12314
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    σ1 激动剂
    4-IBP is a selective ??1 agonist with a high level of affinity for the ??1 receptor (Ki = 1.7 nM) and a moderate affinity for the ??2 receptor (Ki = 25.2 nM) . 了解更多
  12. Carbetocin
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    Carbetocin

    Catalog No. A18080
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    peripheral oxytocin receptors agonist
    Carbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors. 了解更多
  13. Linaclotide
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    Linaclotide

    Catalog No. A13834
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    Guanylate cyclase C 激动剂
    Linaclotide是鸟苷酸环化酶2C的肽激动剂。 了解更多
  14. Capromorelin Tartrate
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    Capromorelin Tartrate

    Catalog No. A21238
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    GHSR agonist
    Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with Ki of 7 nM for hGHS-R1a. 了解更多
  15. Moxonidine Hydrochloride
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    Moxonidine Hydrochloride

    Catalog No. A13416
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    imidazoline receptor 1 激动剂
    Moxonidine Hydrochloride (BDF5895)是咪唑啉1型受体（I1-R）选择性激动剂，为降压剂。 了解更多
  16. Moxonidine HCl
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    Moxonidine HCl

    Catalog No. A11741
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    imidazoline receptor 1 激动剂
    Moxonidine HCl是咪唑啉受体亚型1（I1）的选择性激动剂。Moxonidine引起交感神经系统活动的减少，因此导致血压的降低。 了解更多
  17. Rilmenidine Phosphate
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    Rilmenidine Phosphate

    Catalog No. A14256
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    I(1) imidazoline receptor 激动剂
    Rilmenidine Phosphate是一种选择性的I(1)咪唑啉受体激动剂。 了解更多
  18. Semaglutide
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    Semaglutide

    Catalog No. A18908
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    GLP-1 receptor agonist
    Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes. 了解更多
  19. Lixisenatide
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    Lixisenatide

    Catalog No. A14076
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    GLP-1 receptor 激动剂
    Lixisenatide抑制胰高血糖素释放，显着降低餐后胰高血糖素。对糖尿病（T2DM）有促进作用。 了解更多
  20. BETP
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    BETP

    Catalog No. A13781
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    GLP-1 receptor 激动剂
    BETP是胰高血糖素样肽1（GLP-1）受体的选择性正构构调节剂和部分激动剂。 了解更多
  21. Liraglutide
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    Liraglutide

    Catalog No. A16115
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    GLP-1 receptor 激动剂
    Liraglutide是一种长效胰高血糖素样肽1（GLP-1）受体激动剂。 了解更多
  22. Albiglutide
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    Albiglutide

    Catalog No. A16823
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    GLP-1 激动剂
    Albiglutide是一种胰高血糖素样肽1激动剂（GLP-1激动剂）。 了解更多
  23. Dulaglutide
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    Dulaglutide

    Catalog No. A16987
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    GLP-1 receptor 激动剂
    Dulaglutide是胰高血糖素样肽1（GLP-1）受体激动剂。 了解更多
  24. Strontium ranelate (Protelos)
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    Strontium ranelate (Protelos)

    Catalog No. A11681
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    CaSR 激动剂
    Strontium ranelate是一种抗骨质疏松剂，可增加骨形成并减少骨吸收，从而导致骨转换平衡，有利于骨形成。这类似于胆碱稳定的原硅酸的作用。 了解更多
  25. Evocalcet
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    Evocalcet

    Catalog No. A17003
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    CaSR 激动剂
    Evocalcet是一种钙敏感受体激动剂。钙敏感受体（CaSR）是C类G蛋白偶联受体，可感应细胞外钙离子水平。 了解更多
  26. SB756050
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    SB756050

    Catalog No. A12759
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    TGR5 agonist
    SB756050 is a selective TGR5 agonist currently in phase 1clinical trials for the treatment of type 2 diabetes. 了解更多
  27. INT-777
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    INT-777

    Catalog No. A21168
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    TGR5 agonist
    INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM. 了解更多
  28. INT-767
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    INT-767

    Catalog No. A21494
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    dual FXR/TGR5 agonist
    INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively. 了解更多
  29. TGR5-Receptor-Agonist
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    TGR5-Receptor-Agonist

    Catalog No. A13732
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    TGR5(GPCR19) 激动剂
    TGR5 Receptor Agonist是一种有效的TGR5（GPCR19）激动剂，在U2-OS细胞分析（pEC50 = 6.8）和黑素细胞（pEC50 = 7.5）中显示出增强的效力。 了解更多

产品 201 到 229 共 229个

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