GPCR / G Protein
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AMG-073 HCl (Cinacalcet HCl)
Catalog No. A10219 CaSR activatorAMG-073 HCl(Cinacalcet HCl)是一种用于治疗甲状旁腺功能亢进的化合物,称为拟钙剂,通过增加甲状旁腺钙敏感受体(CaR)对细胞外钙的敏感性来减少甲状旁腺激素(PTH)的合成和分泌 。 了解更多 -
AMG 073 (Cinacalcet)
Catalog No. A11314 -
BAY 41-2272
Catalog No. A15891 -
YC-1 (Lificiguat)
Catalog No. A12402 -
Cinaciguat
Catalog No. A21283 sGC activatorCinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. 了解更多 -
GPR40 Activator 2
Catalog No. A21642 GPR40 activatorGPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. 了解更多 -
GPR40 Activator 1
Catalog No. A21154 GPR40 activatorGPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. 了解更多 -
20(S)-Hydroxycholesterol
Catalog No. A21850 Smo allosteric activator20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多 -
C-DIM12
Catalog No. A15936 -
Mirabegron
Catalog No. A12861 β3 adrenergic receptor activatorMirabegron是一种选择性的beta3-adrenoceptor(β3肾上腺素受体)激动剂,EC50为22.4 nM。是有效的膀胱松弛药和糖尿病药物。 了解更多