GPCR / G Protein

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  1. AMG-073 HCl (Cinacalcet HCl)

    Catalog No. A10219
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    CaSR activator
    AMG-073 HCl(Cinacalcet HCl)是一种用于治疗甲状旁腺功能亢进的化合物,称为拟钙剂,通过增加甲状旁腺钙敏感受体(CaR)对细胞外钙的敏感性来减少甲状旁腺激素(PTH)的合成和分泌 。 了解更多
  2. AMG 073 (Cinacalcet)

    Catalog No. A11314
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    CaSR activator
    AMG 073 (Cinacalcet)是一类治疗甲状旁腺功能亢进的新型化合物。 了解更多
  3. BAY 41-2272

    Catalog No. A15891
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    sGC activator?
    BAY 41-2272是一种直接且不依赖NO的可溶性鸟苷酸环化酶(sGC)刺激物。 了解更多
  4. YC-1 (Lificiguat)

    Catalog No. A12402
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    sGC activator
    YC-1 (Lificiguat)是可溶性胍基环化酶(sGC)的直接活化剂,独立于一氧化氮。 了解更多
  5. Cinaciguat

    Catalog No. A21283
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    sGC activator
    Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. 了解更多
  6. Saikosaponin B2

    Catalog No. A14600
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    Prostanoid activator
    Saikosaponin B2是皂苷激活剂。 了解更多
  7. GPR40 Activator 2

    Catalog No. A21642
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    GPR40 activator
    GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. 了解更多
  8. GPR40 Activator 1

    Catalog No. A21154
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    GPR40 activator
    GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. 了解更多
  9. SRT3190

    Catalog No. A11577
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    SIRT1 activator
    SRT3190是一种强效cxcr2配体。 了解更多
  10. 20(S)-Hydroxycholesterol

    Catalog No. A21850
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    Smo allosteric activator
    20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多
  11. C-DIM12

    Catalog No. A15936
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    Nurr1 activator
    C-DIM12是Nurr1的新型合成活化剂。C-DIM12诱导多巴胺能基因表达,并在体外防御6-羟基多巴胺的神经毒性。 了解更多
  12. Mirabegron

    Catalog No. A12861
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    β3 adrenergic receptor activator
    Mirabegron是一种选择性的beta3-adrenoceptor(β3肾上腺素受体)激动剂,EC50为22.4 nM。是有效的膀胱松弛药和糖尿病药物。 了解更多

12 个项目

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