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CID16020046
Catalog No. A16818 GPR55 拮抗剂CID16020046是一种选择性的GPR55拮抗剂，在酵母中抑制GPR55的组成活性，IC50为150 nM。它对其他广谱GPCRs、离子通道、激酶和核受体表现出弱活性。 了解更多 -
Aglafoline
Catalog No. A12257 PAF antagonistAglafoline is an effective PAF antagonist not only in vitro, but also in vivo. 了解更多 -
Foropafant
Catalog No. A13388 PAF receptor antagonistForopafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet-activating factor (PAF) receptor. 了解更多 -
Ginkgolide B
Catalog No. A10429 -
48740 RP
Catalog No. A12339 -
Macitentan
Catalog No. A11492 Endothelin receptor 拮抗剂Macitentan是一种口服活性非肽双重ETA/ETB(内皮素) receptor双重拮抗剂，IC50为0.5 nM/391 nM。用于治疗特发性肺纤维化(IPF)和肺动脉高压(PAH)。 了解更多 -
Endothelin Mordulator 1
Catalog No. A13040 endothelin receptor modulatorEndothelin Mordulator 1 is a endothelin receptor modulator, used for the research of endothelin-mediated disorders. 了解更多 -
Sparsentan
Catalog No. A20879 angiotensin II and endothelin A receptor antagonistSparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. 了解更多 -
Tezosentan
Catalog No. A21118 endothelin (ET) receptor antagonistTezosentan (RO 610612) is an endothelin (ET) receptor antagonist, with pA2s of 9.5, 7.7 for ETA and ETB receptors, respectively. 了解更多 -
Darusentan
Catalog No. A21280 endothelin A (ETA) receptor antagonistDarusentan is a selective endothelin A (ETA) receptor antagonist. 了解更多 -
Macitentan (n-butyl analogue)
Catalog No. A21845 endothelin ETA and ETB receptor antagonistMacitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH). 了解更多 -
Aprocitentan
Catalog No. A21999 dual ETA/ETB antagonistAprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively. 了解更多 -
Zibotentan (ZD4054)
Catalog No. A11006 ETA-receptor 拮抗剂Zibotentan (ZD4054)是一种有效且特异性的ETA受体（内皮素A受体）拮抗剂（IC50 = 21 nM），对ETB没有抑制活性。 了解更多 -
Bosentan
Catalog No. A11091 -
Ambrisentan (BSF 208075)
Catalog No. A11291 EndothelinA receptor 拮抗剂Ambrisentan (BSF 208075)充当内皮素受体拮抗剂，对A型内皮素受体（ETA）具有选择性。 了解更多 -
Avosentan (SPP301)
Catalog No. A11301 -
Sitaxsentan sodium (TBC-11251)
Catalog No. A11564 ETA receptor 拮抗剂Sitaxsentan sodium (TBC-11251)是一种选择性内皮素受体A拮抗剂，IC50和Ki分别为1.4 nM和0.43 nM。 了解更多 -
Atrasentan
Catalog No. A13779 ETA 拮抗剂Atrasentan是一种实验药物，正在研究中，用于治疗各种类型的癌症，包括非小细胞肺癌。它是对A型亚型（ETA）有选择性的内皮素受体拮抗剂,对ETA的IC50为0.0551 nM。 了解更多 -
Endothelin-2, human
Catalog No. A14894 Endothelin-2, human是人的内源肽，主要存在于肾脏和肠中。对ETA和ETB内皮素受体具有相似的选择性。 了解更多 -
Atrasentan HCl
Catalog No. A15007 Endothelin 拮抗剂 receptorAtrasentan hydrochloride是一种开发用于治疗前列腺癌的内皮素拮抗剂受体（IC50 = 0.0551 nM，ETA）。 了解更多 -
BQ-123
Catalog No. A15912 -
Bosentan Hydrate
Catalog No. A14944 -
Radioprotectin-1
Catalog No. A18628 LPA2 agonistRadioprotectin-1 is a potent and specific nonlipid agonist of lysophosphatidic acid receptor 2 (LPA2), with an EC50 value of 25 nM for murine LPA2 subtype. 了解更多 -
ONO-7300243
Catalog No. A16644 LPA1 antagonistONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM. 了解更多 -
LPA1 antagonist 1
Catalog No. A21301 LPA1 antagonistLPA1 antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC50 of 25 nM. 了解更多 -
LPA2 antagonist 1
Catalog No. A21308 -
BMS-986020 sodium
Catalog No. A21842 LPA1 antagonistBMS-986020 sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist. 了解更多 -
Ki16198
Catalog No. A11966 -
AM095 free base
Catalog No. A14180 LPA1 Receptor 拮抗剂AM095 free base是一种新型，有效且口服可生物利用的溶血磷脂酸1型受体（LPA1）拮抗剂，对小鼠或重组人LPA1的IC50值分别为0.73和0.98μM。 了解更多 -
GRI 977143
Catalog No. A15343 -
GSK-269984A
Catalog No. A17096 -
Tafluprost
Catalog No. A17442 prostaglandin analogueTafluprost, also known as MK2452 and AFP-168, is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. 了解更多 -
Benorylate
Catalog No. A17501 Prostaglandin Receptor inhibitorBenorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. 了解更多 -
Dinoprost tromethamine
Catalog No. A17505 Prostaglandin Receptor inhibitorDinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. 了解更多
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