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VPC 23019
Catalog No. A20102 S1P antagonistVPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively). 了解更多 -
FTY720 (S)-Phosphate
Catalog No. A21324 S1PR1 agonistFTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury. 了解更多 -
PF429242 dihydrochloride
Catalog No. A21386 S1P inhibitorPF429242 dihydrochloride is a reversible and competitive S1P inhibitor with an IC50 of 175 nM. 了解更多 -
FTY720 (Fingolimod)
Catalog No. A10408 S1P Receptor 拮抗剂FTY720 (Fingolimod)是ISP-1(肉豆蔻酸)的衍生物，ISP-1是中国草药Iscaria sinclarii的真菌代谢物，也是鞘氨醇的结构类似物。 了解更多 -
BAF312 (Siponimod)
Catalog No. A12906 -
PF-543
Catalog No. A13039 -
CYM 5442 HCl
Catalog No. A13637 -
PF-543 Citrate
Catalog No. A15210 SphK1 抑制剂PF-543 Citrate是一种新型的SphK1细胞渗透抑制剂，K（i）为3.6 nM，PF-543具有鞘氨醇竞争性，对SphK1的选择性是SphK2同种型的100倍以上。 了解更多 -
RPC1063 (Ozanimod)
Catalog No. A15819 -
NS13001
Catalog No. A15833 -
Ponesimod
Catalog No. A13307 -
KRP-203
Catalog No. A13308 -
Fingolimod
Catalog No. A17798 S1P antagonistFingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant. 了解更多 -
CGRP 8-37 (human)
Catalog No. A16949 CGRP receptor 拮抗剂CGRP 8-37 (human)是人降钙素基因相关肽（hCGRP）片段，也是CGRP受体的拮抗剂。序列：Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn- Val-Gly-Ser-Lys-Ala-Phe；VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF。 了解更多 -
Olcegepant
Catalog No. A11512 CGRP1 receptorOlcegepant is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP. 了解更多 -
Ubrogepant
Catalog No. A21670 CGRP antagonistUbrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. 了解更多 -
Olcegepant hydrochloride
Catalog No. A21900 CGRP1 receptor antagonistOlcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. 了解更多 -
MK 3207 HCl
Catalog No. A10598 CGRP Receptor 拮抗剂MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂，IC50为0.12 nM。 了解更多 -
MK-0974 (Telcagepant)
Catalog No. A11255 -
BMS-927711
Catalog No. A13102 CGRP receptor 拮抗剂BMS-927711是一种有效的，选择性的，竞争性的人降钙素基因相关肽（CGRP）受体拮抗剂，已显示出体内功效，而没有血管收缩作用。 了解更多 -
Mozavaptan
Catalog No. A16622 nonpeptide vasopressin V2 receptor antagonistMozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. 了解更多 -
Lixivaptan
Catalog No. A21279 vasopressin receptor V2 antagonistLixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively. 了解更多 -
Desmopressin
Catalog No. A12351 Desmopressin是一种合成的加压素类似物，在V1B和V2受体上起激动剂的作用(EC50值分别为11.4和23.9 nM，Ki值分别为5.84和65.9 nM)。 了解更多 -
Vasopressin antagonist 1867
Catalog No. A16188 V1b receptor 拮抗剂Vasopressin antagonist 1867，可口服和选择性V1b受体拮抗剂（hV1b抑制作用的IC50值为3 nM，相对于hV1a，hV2和hOT表现出> 1000倍的选择性）。 了解更多 -
Sigma-1 receptor antagonist 2
Catalog No. A18504 sigma 1 receptor antagonistSigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (??1 R) antagonist with Kis of 3.88 and 1288 nM for ??1 and ??2 receptor, respectively. 了解更多 -
Sigma-1 receptor antagonist 3
Catalog No. A18501 Sigma-1 receptor antagonistSigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (??1) receptor antagonist with a Ki of 1.14 nM. 了解更多 -
Cutamesine
Catalog No. A21152 sigma 1 receptor agonistCutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(??1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4??1.9 nM); 100-fold less affinity for the sigma 2 receptor. 了解更多 -
Ditolylguanidine
Catalog No. A21268 Sigma receptor agonistDitolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (??1/??2 receptor). 了解更多 -
Siramesine Hydrochloride
Catalog No. A12479 Sigma-2 receptor 激动剂Siramesine Hydrochloride是一种选择性sigma-2受体激动剂，已被证明可触发癌细胞的细胞死亡并在体内表现出强大的抗癌活性。 了解更多 -
S1RA (E-52862)
Catalog No. A12504 sigma-1 receptor 拮抗剂S1RA是一种选择性sigma-1受体拮抗剂，据报道其结合亲和力为Ki = 17.0±7.0 nM，对sigma-2受体具有选择性，并且对其他170种受体，酶，转运蛋白和离子通道具有选择性。 了解更多 -
Siramesine
Catalog No. A13036 -
BD-1047 2HBr
Catalog No. A13196 -
Glycerol phenylbutyrate
Catalog No. A18201 sigma-2 (σ2) receptor ligandGlycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. 了解更多 -
Carbetocin
Catalog No. A18080 peripheral oxytocin receptors agonistCarbetocin (Lonactene; Duratocin) is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth; an agonist at peripheral oxytocin receptors. 了解更多 -
L-371,257
Catalog No. A21219 oxytocin receptor antagonistL-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM). 了解更多
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