GPCR / G Protein
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Pramipexole dihydrochloride monohyrate
Catalog No. A10747 Dopamine Receptor 激动剂Pramipexole dihydrochloride monohyrate是非麦角灵类的多巴胺激动剂,适用于治疗早期帕金森氏病(PD)和不安腿综合征(RLS)。 了解更多 -
B-HT 920 2HCl
Catalog No. A11341 -
Lurasidone (SM13496)
Catalog No. A11214 Dopamine D2 抑制剂Lurasidone (SM-13496)是dopamine D2和5-HT7的拮抗剂,IC50 值分别为 1.68 和 0.495 nM。Lurasidone (SM-13496) 也是 5-HT1A 受体的部分激动剂。 了解更多 -
GBR-12935 2HCl
Catalog No. A11937 -
Domperidone
Catalog No. A10329 Domperidone是一种多巴胺受体抑制剂,是一种抗多巴胺试剂。 了解更多 -
Dopamine hydrochloride
Catalog No. A10331 Dopamine hydrochloride (abbreviated as DA)是儿茶酚胺家族中的一种简单的有机化学物质,是一种单胺类神经递质,一种由神经细胞释放以向其他神经细胞发送信号的化学物质。 了解更多 -
Haloperidol (Haldol)
Catalog No. A10446 -
Rotigotine
Catalog No. A11553 -
Paliperidone
Catalog No. A10691 Dopamine Receptor 拮抗剂Paliperidone (Invega)是一种非典型的抗精神病药。 了解更多 -
Naxagolide
Catalog No. A13087 -
ent Naxagolide Hydrochloride
Catalog No. A13089 dopamine D2-receptor 激动剂ent Naxagolide Hydrochloride是一种多巴胺D2受体激动剂,用于治疗锥体外系疾病。该化合物是抗帕金森病药物。 了解更多 -
Pramipexole dihydrochloride
Catalog No. A12536 Pramipexole dihydrochloride是对D3受体表现出选择性的多巴胺受体激动剂。 了解更多 -
cis-(Z)-Flupentixol dihydrochloride
Catalog No. A12347 Dopamine receptor 拮抗剂cis-(Z)-Flupentixol dihydrochloride是多巴胺受体拮抗剂、抗精神病药物、抗精神病药物。 了解更多 -
GBR 12783 dihydrochloride
Catalog No. A13128 dopamine uptake 抑制剂GBR 12783 dihydrochloride是一种非常有效的选择性多巴胺摄取抑制剂(抑制大鼠纹状体突触体中[3H]-多巴胺摄取的IC50为1.8 nM)。 了解更多 -
Pergolide Mesylate
Catalog No. A14179 -
SB269652
Catalog No. A14191 -
Metoclopramide HCl
Catalog No. A14247 dopamine D2 receptor 拮抗剂Metoclopramide HCl是一种选择性的多巴胺D2受体拮抗剂。 了解更多 -
(+) PD 128907
Catalog No. A14376 Dopamine receptor 激动剂(+)-PD 128907 hydrochloride是一种有效的D3DR(多巴胺受体)激动剂(Ki = 2.3 nM)。 了解更多 -
Bromocriptin mesylate
Catalog No. A13705 dopamine D2 receptor 激动剂Bromocriptin mesylate是一种有效的多巴胺受体激动剂,它以最高的亲和力(Ki = 2.5 nM)与D2受体结合。 了解更多 -
Brexpiprazole
Catalog No. A13527 D2 dopamine partial 激动剂Brexpiprazole是一种新型的D2多巴胺部分激动剂研究产品,目前正在临床试验中,用于治疗抑郁症,精神分裂症和注意缺陷多动障碍(ADHD)。 了解更多 -
Dexpramipexole dihydrochloride
Catalog No. A15066 -
rac-Rotigotine Hydrochloride
Catalog No. A15217 -
Amineptine
Catalog No. A14998 Amineptine是一种三环抗抑郁药物,可选择性地阻断3H-imipramine结合,吸收多巴胺,并结合临床状态的变化对主要抑郁症患者的血小板进行了研究。 了解更多 -
SCH 23390 HCl
Catalog No. A13066 -
C-DIM12
Catalog No. A15936 -
Tetrabenazine (Xenazine)
Catalog No. A10919 Tetrabenazine (Xenazine)是用于过度运动障碍的对症治疗药物。 了解更多 -
ACR 16 hydrochloride
Catalog No. A16074 dopaminergic stabilizerACR 16 hydrochloride是一种多巴胺能稳定剂(对于D2(低)和D2(高),Ki值分别为17550 nM和7521),通过功能性多巴胺D2受体拮抗作用和皮质谷氨酸功能的双重作用,稳定地稳定精神运动活动。在各种情况下神经传递受到干扰。 了解更多 -
UNC 9994 hydrochloride
Catalog No. A16087 dopamine D2 receptor 激动剂UNC 9994 hydrochloride,独特的,β-arrestin偏向的功能选择性多巴胺D2受体(D2R)激动剂(Ki值为30 nM;在ε-arrestin-2募集试验中EC50值为50 nM),在体内具有抗精神病活性。UNC9994在野生型小鼠中显着抑制了PCP诱导的超运动,而在Δr-arrestin-2基因敲除小鼠中这种作用被完全消除。 了解更多 -
Prochlorperazine
Catalog No. A16172 -
Alizapride HCl
Catalog No. A16394 -
Azaperone
Catalog No. A16416 -
Melitracen hydrochloride
Catalog No. A17494 dopamine D1/2 receptor antagonistMelitracen HCl ia potential dopamine D1/2 receptor antagonist used to treat depression. It is often co-administered with flupenthixol as a treatment for trigeminal neuralgia. It does not effect cardiovascular function. 了解更多 -
Metoclopramide hydrochloride hydrate
Catalog No. A18072 Dopamine D2 antagonistMetoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. 了解更多 -
NRA-0160
Catalog No. A20128 Dopamine D4 receptor antagonistNRA-0160 is a selective dopamine D4 receptor antagonist, with a Ki value of 0.48 nM and with negligible affinity for dopamine D2 receptor (Ki: >10000 nM), D3 receptor (Ki: 39 nM), rat 5-HT2A receptor (Ki: 180 nM) and rat α1 adrenoceptor (Ki: 237 nM). 了解更多 -
Dicarbine
Catalog No. A18925 Dopamine receptor blockerDicarbine blocks dopamine receptors in various brain parts and prevents the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. Dicarbine could be used to treat patients with schizophrenia and alcoholic psychosis in clinical. 了解更多