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Methylnaltrexone Bromide
Catalog No. A15159 -
TRV130 HCl (Oliceridine)
Catalog No. A15444 u-opioid receptor 激动剂TRV130 HCl (Oliceridine)是一种新型的μ-opioid 受体（MOR）G蛋白偏向配体。诱导强大的G蛋白信号传导（pEC50 = 8.1），效力和功效与吗啡相似，但β-arrestin募集和受体内在化作用要低得多。 了解更多 -
GSK1521498 free base
Catalog No. A18994 μ-opioid receptor antagonistGSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs. 了解更多 -
CYT-1010 hydrochloride
Catalog No. A21348 mu-opioid receptor agonistCYT-1010 hydrochloride is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. 了解更多 -
GSK1521498 free base (hydrochloride)
Catalog No. A21792 μ-opioid receptor (MOR) antagonistGSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. 了解更多 -
AR-M 1000390 hydrochloride
Catalog No. A21911 δ opioid receptor agonistAR-M 1000390 hydrochloride is an exceptionally selective, potent δ opioid receptor agonist with an EC50 of 7.2??0.9 nM for δ agonist potency. 了解更多 -
ADL5859 HCl
Catalog No. A11072 Opioid Receptor 激动剂ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。 了解更多 -
MCOPPB 3HCl
Catalog No. A10561 -
BRL 52537 HCl
Catalog No. A11210 Opioid Receptors 激动剂BRL 52537 hydrochloride是一种高度选择性和有效的κ阿片类激动剂（Ki = 0.24 nM）。比吗啡强25倍。 了解更多 -
Alvimopan (ADL 8-2698)
Catalog No. A11292 Opioid 拮抗剂Alvimopan (ADL 8-2698)表现为外周作用的opioid拮抗剂，Alvimopan竞争性结合胃肠道中的mu-opioid receptor。 了解更多 -
Nalfurafine hydrochloride
Catalog No. A12579 opioid κ-selective 激动剂Nalfurafine hydrochloride是一种κ-opioid激动剂。 了解更多 -
U-69593
Catalog No. A14187 -
Alvimopan dihydrate
Catalog No. A14991 ?-opioid receptor 激动剂Alvimopan dihydrate (LY 246736,ADL 8-2698)是一种外周作用的类阿片受体（PAM-OR，IC50 = 1.7 nM）拮抗剂，可促进术后胃肠道恢复。 了解更多 -
Alvimopan monohydrate
Catalog No. A14992 ?-opioid receptor 激动剂Alvimopan monohydrate是一种外围作用的类阿片受体（PAM-OR，IC50 = 1.7 nM）拮抗剂，可促进术后肠胃的恢复。 了解更多 -
Naloxegol Oxalate
Catalog No. A15972 -
Docusate Sodium
Catalog No. A16155 Docusate Sodium是一种用于治疗便秘的泻药，对于便秘，由于使用了鸦片制剂，可能与刺激性泻药一起使用，可以通过口腔或直肠服用。 了解更多 -
Cebranopadol (GRT-6005)
Catalog No. A12670 Opioid Receptor 激动剂Cebranopadol是一种有效的伤害感受器/孤儿蛋白FQ肽（NOP）和阿片受体激动剂。作用于人NOP，MOP，KOP 和δ-阿片肽(DOP)受体，Ki/EC50 分别为 0.9 nM/13 nM，0.7 nM/1.2 nM，2.6 nM/17 nM，18 nM/110 nM。 了解更多 -
Bevenopran
Catalog No. A17110 opioid receptor antagonisBevenopran，也称为CB-5945，ADL-5945，MK-2402，OpRA III，是一种外周选择性μ-和δ-阿片样物质受体拮抗剂。 了解更多 -
Trimebutine maleate
Catalog No. A18115 ?- opioid receptor agonistTrimebutine Maleate is a drug with antimuscarinic and weak mu opioid agonist effects. Trimebutine Maleate modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome. 了解更多 -
BTRX-335140
Catalog No. A18583 κ opioid receptor antagonistBTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. 了解更多 -
MTEP hydrochloride
Catalog No. A15174 -
CBiPES HCl
Catalog No. A15811 -
BMT-145027
Catalog No. A12457 mGluR5 positive allosteric modulatorBMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM. 了解更多 -
Lu AF21934
Catalog No. A12140 mGlu4 receptor modulatorLu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4. 了解更多 -
Dipraglurant
Catalog No. A11382 mGluR5 antagonistsDipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. 了解更多 -
O-Phospho-L-serine
Catalog No. A21159 group III mGluR receptors agonistO-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. 了解更多 -
Mavoglurant
Catalog No. A21223 mGlu5 receptor antagonistMavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5. 了解更多 -
Basimglurant
Catalog No. A21225 mGlu5 negative allosteric modulatorBasimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. 了解更多 -
Mavoglurant racemate
Catalog No. A21799 mGlu5 receptor antagonistMavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. 了解更多 -
(R)-ADX-47273
Catalog No. A21887 mGluR5 positive allosteric modulator(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . 了解更多 -
Methoxy-PEPy
Catalog No. A21899 mGlu5 receptor antagonistMethoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM. 了解更多 -
(1R,2S)-VU0155041
Catalog No. A21933 partial mGluR4 agonist(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. 了解更多 -
CHPG sodium salt
Catalog No. A21968 mGluR5 agonistCHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. 了解更多
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