A 438079 hydrochloride

Name: A 438079 hydrochloride
SKU: A14983

目录号: A14983

P2X7 receptor 拮抗剂

Product Citations (1)

A 438079 hydrochloride Chemical Structure

CAS NO. 899431-18-6

A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂（抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9）。

库存：现货

规格	价格	数量
10 mg	￥ 665.00
25 mg	￥ 1,505.00
50 mg	￥ 2,765.00

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生物活性

A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂（抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9）。

靶点信息

P2X7 receptor
6.9(pIC50)

溶解度 *

In vitro (25°C)	DMSO	55 mg/mL (160.53 mM)
	Water	55 mg/mL (160.53 mM)
	Ethanol	Warmed: 18 mg/mL (52.53 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.19 mL	145.94 mL	291.88 mL
0.5 mM	5.84 mL	29.19 mL	58.38 mL
1 mM	2.92 mL	14.59 mL	29.19 mL
5 mM	0.58 mL	2.92 mL	5.84 mL

*The above data is based on the productmolecular weight 342.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14983
作用机制	Antagonist (拮抗剂)
M. Wt	342.61
Formula	C13H10Cl3N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	899431-18-6
SMILES	C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl