产品详情
ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 14 nM.
In vitro | DMSO | 96 mg/mL (189.2 mM) | |
Water | Insoluble | ||
Ethanol | 96 mg/mL (189.2 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.71 mL | 98.54 mL | 197.09 mL |
0.5 mM | 3.94 mL | 19.71 mL | 39.42 mL |
1 mM | 1.97 mL | 9.85 mL | 19.71 mL |
5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 507.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A18652 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 507.39 |
Formula | C20H22F9N3O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1446817-84-0 |
Synonyms | ABX-1431; ABX 1431; ABX1431; |
SMILES | O=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2N3CCCC3)CC1)OC(C(F)(F)F)C(F)(F)F |
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