Actinomycin D

目录号: A13239

Actinomycin D

Actinomycin D Chemical Structure

CAS NO. 50-76-0

Actinomycin D是从小链霉菌中分离出来的一种代谢产物,与DNA的GpC步骤结合。抑制 DNA 修复,IC50 为 0.42 μM。该化合物可作为抗生素,并且比革兰氏阴性细菌更有效地抵抗革兰氏阳性细菌。

库存: 现货

规格 价格 数量
10 mg
¥ 560.00
25 mg
¥ 1,400.00
50 mg
¥ 1,960.00
100 mg
¥ 3,360.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Actinomycin D是从小链霉菌中分离出来的一种代谢产物,与DNA的GpC步骤结合。抑制 DNA 修复,IC50 为 0.42 μM。该化合物可作为抗生素,并且比革兰氏阴性细菌更有效地抵抗革兰氏阳性细菌。
In vitro DMSO 91 mg/mL (72.48 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.97 mL 39.83 mL 79.66 mL
0.5 mM 1.59 mL 7.97 mL 15.93 mL
1 mM 0.8 mL 3.98 mL 7.97 mL
5 mM 0.16 mL 0.8 mL 1.59 mL

*The above data is based on the productmolecular weight 1255.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13239
M. Wt 1255.4
Formula C62H86N12O16
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 50-76-0
Synonyms Actinomycin-D
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C

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