Adrenergic Receptors
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Atipamezole HCl
Catalog No. A13902 α2 adrenergic receptor 拮抗剂Atipamezole hydrochloride是一种选择性α2肾上腺素受体拮抗剂(α2A、α2B、α2C、α1A和α1B受体的Ki值分别为1.1、1.0、0.89、1300和6500nm)。已经被证明是大脑的渗透剂。 了解更多 -
Dexmedetomidine HCl
Catalog No. A11846 alpha2-adrenoceptor 激动剂Dexmedetomidine hydrochloride是美托咪啶的活性异构体,它充当有效的,高度选择性的α2-AR(α2-肾上腺素受体)激动剂。 了解更多 -
Medetomidine HCl
Catalog No. A13775 adrenergic alpha-2 receptor 激动剂Medetomidine Hydrochloride是一种肾上腺素α2-受体激动剂,Ki为1.08 nM,比作用于α1-adrenoceptor选择性高1620倍。由于其镇痛和镇静作用而被用于兽医学。 了解更多 -
CL 316243 disodium salt
Catalog No. A13657 β3 adrenergic 激动剂CL 316243 disodium salt是一种3β-肾上腺素能激动剂,被开发为一种抗肥胖和糖尿病的药物,并使小鼠的血糖水平迅速下降。 了解更多 -
BRL 37344 Na Salt
Catalog No. A13676 -
Celiprolol HCl
Catalog No. A13623 adrenergic receptor 拮抗剂Celiprolol HCl是一种b1肾上腺素能受体拮抗剂和b2肾上腺素能受体局部激动剂,在体外显示其ED50值为40-50 uM可使人的动脉和静脉松弛。 了解更多 -
Guanabenz acetate
Catalog No. A13635 -
BRL 44408 maleate
Catalog No. A13399 -
HEAT hydrochloride (BE 2254)
Catalog No. A13408 Adrenergic α1 Receptor 拮抗剂HEAT hydrochloride (BE 2254)是一种选择性很强的α1-肾上腺素受体拮抗剂,是3-[125I]-衍生物的前体。肾上腺素受体或肾上腺素能受体是参与多种交感神经系统过程的G蛋白偶联受体。 了解更多 -
Idazoxan Hydrochloride
Catalog No. A13409 α2- adrenoceptor 拮抗剂 / I2 imidazoline receptor 激动剂Idazoxan hydrochloride 是α2-AR肾上腺素受体拮抗剂和潜在I2咪唑啉受体激动剂。还显示I1咪唑啉受体拮抗剂活性。(I1、I2和α的公钥基础设施值分别为5.90、7.22、8.01、7.43和7.7)。 了解更多 -
NAN-190 hydrobromide
Catalog No. A13417 5-HT1A receptor 拮抗剂NAN-190 hydrobromide是一种广泛用于科学研究的药物和研究化学品。以前认为它是一种选择性的5-HT1A受体拮抗剂,但后来的发现表明它也能有效地阻断α2肾上腺素能受体。 了解更多 -
Phentolamine HCl
Catalog No. A13421 -
Rauwolscine
Catalog No. A13426 -
S-(-)-Atenolol
Catalog No. A13427 -
S(-)-Propranolol HCl
Catalog No. A13428 β-adrenergic blockerS(-)-Propranolol HCl是一种非选择性的β-肾上腺素能受体(βAR)拮抗剂,对β1AR和β2AR具有高亲和力,Ki值分别为1.8 nM和0.8 nM。 盐酸普萘洛尔抑制[3H] -DHA与大鼠脑膜制剂的结合,IC50为12 nM。 了解更多 -
(S)-Timolol maleate
Catalog No. A13429 -
Tulobuterol
Catalog No. A13432 -
UK 14,304 tartrate
Catalog No. A13433 -
Xylazine HCl
Catalog No. A13434 -
Tamsulosin hydrochloride
Catalog No. A14936 -
(R,R)-Formoterol
Catalog No. A14964 -
Guanfacine hydrochloride
Catalog No. A15098 α2A-adrenoceptor 激动剂Guanfacine hydrochloride是一种抗高血压药,是一种选择性的α2A肾上腺素受体激动剂,Kd为31 nM,选择性是α2B肾上腺素受体的60倍。 了解更多 -
HOKU-81
Catalog No. A15117 -
Asenapine HCl
Catalog No. A15002 adrenergic receptor/5-HT receptor 抑制剂Asenapine hydrochloride抑制肾上腺素能受体(α1,α2A,α2B,α2C)的Ki为0.25-1.2 nM,还抑制5-HT受体(1A,1B,2A,2B,2C,5A,6、7),Ki为0.03- 4.0 nM。 了解更多 -
Desvenlafaxine succinate hydrate
Catalog No. A15491 serotonin (5-HT)/norepinephrine (NE) reuptake 抑制剂Desvenlafaxine succinate hydrate是一种新型5-羟色胺(5-HT)转运蛋白 和去甲肾上腺素(NE)转运蛋白重吸收抑制剂,Ki值分别为40.2 nM和558.4 nM 了解更多 -
Pardoprunox HCl (SLV-308)
Catalog No. A11538 Pardoprunox HCl (SLV-308)是一种抗帕金森病药物,是多巴胺受体D2、D3和5-HT1A激动剂,用于治疗帕金森病。 了解更多 -
ICI-118551
Catalog No. A15878 β2 adrenergic receptor 拮抗剂ICI-118551是选择性的β2肾上腺素能受体(肾上腺素受体)拮抗剂。 了解更多 -
Vilanterol trifenatate
Catalog No. A15998 β2-adrenergic receptor 激动剂Vilanterol trifenatate是一种长效的β-2激动剂药物,于2013年5月与葛兰素氟替卡松合用,获葛兰素史克(Brax Elmitta)出售为Breo Ellipta,用于治疗慢性阻塞性肺疾病(COPD)。 了解更多 -
Brimonidine Tartrate
Catalog No. A15033 α-adrenergic receptor 激动剂Brimonidine Tartrate是一种高度选择性的α-肾上腺素能受体激动剂,对α2A肾上腺素能受体的EC50为0.45 nM。 了解更多 -
Acebutolol HCl
Catalog No. A16387 -
Clorprenaline HCl
Catalog No. A16465 -
Vilanterol
Catalog No. A13125 ultra-long-acting β? adrenoreceptor 激动剂Vilanterol是一种新的选择性β2-AR激动剂,PEC50值为10.37±0.05。 了解更多 -
Urapidil
Catalog No. A17074 -
Methoxamine HCl
Catalog No. A17365 alpha-1 adrenergic agonistMethoxamine Hydrochloride is an alpha-1 adrenergic agonist that causes prolonged peripheral vasoconstriction. 了解更多 -
Nifenalol HCl
Catalog No. A17246 beta-adrenergic receptor antagonistNifenalol, also known as INPEA, is a new beta-adrenergic receptor antagonist. 了解更多 -
Ractopamine HCl
Catalog No. A17372 beta-Adrenergic agonistRactopamine HCl is a beta-Adrenergic agonist. It acts by being a full agonist at the TAAR1. 了解更多 -
Moxisylyte hydrochloride
Catalog No. A17725 alpha-adrenergic blocking agentMoxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. 了解更多 -
Midodrine hydrochloride
Catalog No. A17757 Adrenergic alpha-1 agonistMidodrine hydrochloride is an ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of hypotension. It improves clinical outcome of chronic hypotension. 了解更多 -
Doxazosin
Catalog No. A17779 α-1 adrenergic receptor blockerDoxazosin is an α-1 adrenergic receptor blocker that inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. Blockages of the alpha-1 adrenergic action on the vascular smooth muscles lead to a decrease in vascular resistance and antihypertensive activity. 了解更多 -
Brimonidine
Catalog No. A17899 α2-adrenergic receptor agonistBrimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist. 了解更多 -
Nylidrin Hydrochloride
Catalog No. A17947 beta-adrenergic agonistNylidrin hydrochloride is a beta-adrenergic agonist. Nylidrin hydrochloride is shown to be an effective inhibitor of IgE-mediated release of histamine from human basophils, and thus can be used as antiallergic agent. 了解更多 -
Metipranolol hydrochloride
Catalog No. A18064 β-adrenergic receptor antagonistMetipranolol (hydrochloride) is a non-selective β-adrenergic receptor (β-AR) antagonist. Formulations containing metipranolol have been used in the treatment of elevated IOP in patients with ocular hypertension or glaucoma. 了解更多 -
Anisodamine
Catalog No. A18215 alpha-1 adrenergic receptors / mAChRs inhibitorAnisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. 了解更多