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AG-24322是第二代CDK抑制剂。AG-024322是有效的CDK1，CDK2和CDK4抑制剂，可在临床前模型中产生细胞周期停滞和抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.9 mL | 119.49 mL | 238.98 mL |
| 0.5 mM | 4.78 mL | 23.9 mL | 47.8 mL |
| 1 mM | 2.39 mL | 11.95 mL | 23.9 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
*The above data is based on the productmolecular weight 418.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15485 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 418.44 |
| Formula | C23H20F2N6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 837364-57-5 |
| Synonyms | AG024322, AG-024322 |
| SMILES | CCNCC1=C(C(=CN=C1)C2=CC3=C(C=C2)NNC3=C4N=C5C=C(C=C(C5=N4)F)F)C |
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