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AG-1288是酪氨酸激酶抑制剂。已显示在人羊膜细胞（IC50 = 21 mM）中，可阻断糖皮质激素诱导的细胞毒性，TNFα诱导的细胞毒性和糖皮质激素诱导的COX-2活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.25 mL | 216.26 mL | 432.53 mL |
| 0.5 mM | 8.65 mL | 43.25 mL | 86.51 mL |
| 1 mM | 4.33 mL | 21.63 mL | 43.25 mL |
| 5 mM | 0.87 mL | 4.33 mL | 8.65 mL |
*The above data is based on the productmolecular weight 231.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13587 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 231.2 |
| Formula | C10H5N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 116313-73-6 |
| Synonyms | AG1288, AG 1288, Tyrphostin AG 1288 |
| SMILES | C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N |
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