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AG 957是有效的酪氨酸激酶抑制剂。与p140c-abl（Ki = 10μM）相比，选择性阻断人p210bcr-abl（Ki = 750 nM）的酪氨酸激酶活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.59 mL | 182.96 mL | 365.93 mL |
| 0.5 mM | 7.32 mL | 36.59 mL | 73.19 mL |
| 1 mM | 3.66 mL | 18.3 mL | 36.59 mL |
| 5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
*The above data is based on the productmolecular weight 273.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13589 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 273.28 |
| Formula | C15H15NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 140674-76-6 |
| Synonyms | Lavendustin C Analog, AG-957, AG957 |
| SMILES | COC(=O)C1=CC=C(C=C1)NCC2=C(C=CC(=C2)O)O |
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