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Alvimopan dihydrate (LY 246736,ADL 8-2698)是一种外周作用的类阿片受体（PAM-OR，IC50 = 1.7 nM）拮抗剂，可促进术后胃肠道恢复。
| In vitro | DMSO | 79 mg/mL (171.52 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.71 mL | 108.56 mL | 217.13 mL |
| 0.5 mM | 4.34 mL | 21.71 mL | 43.43 mL |
| 1 mM | 2.17 mL | 10.86 mL | 21.71 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.34 mL |
*The above data is based on the productmolecular weight 460.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14991 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 460.56 |
| Formula | C25H36N2O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 170098-38-1 |
| Synonyms | LY 246736 dihydrate, ADL 8-2698 dihydrate |
| SMILES | CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O.O.O |
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