微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
AMG-925是一种有效，选择性和生物利用性的FLT3/细胞周期蛋白依赖性激酶4（CDK4）双激酶抑制剂。
靶点信息
| FLT3 | CDK4 | CDK1 | ||
| 1 nM | 3 nM | 2.22 μM |
| In vitro (25°C) | DMSO | 0.01 mg/mL (0.02 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | Insoluble | ||
| In vivo | 2% hydroxypropyl methylcellulose+1% Tween 80 | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.03 mL | 212.07 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.41 mL |
| 1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
*The above data is based on the productmolecular weight 471.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14025 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 471.55 |
| Formula | C26H29N7O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1401033-86-0 |
| Synonyms | AMG925, AMG 925 |
| SMILES | CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5 |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Cyt387 (Momelotinib)
Cyt387 (Momelotinib)是Janus激酶JAK1和JAK2的抑制剂，可作为ATP竞争者，IC50值分别为11和18 nM。
Decernotinib
Decernotinib是Vertex开发的口服选择性Janus激酶3（JAK3）抑制剂。
SGI-1776 (free base)
SGI-1776 (free base)是Pim1的一种新型ATP竞争性抑制剂，在无细胞试验中的IC50为7 nM，选择性是Pim2和Pim3的50倍和10…
Keywords:购买 AMG-925 | AMG-925 供应商 | 订购 AMG-925 | AMG-925 价格 | AMG-925 生产商 | 订单 AMG-925 | AMG-925 代理商 | 购买 1401033-86-0| 1401033-86-0 供应商 | 订购 1401033-86-0 | 1401033-86-0 价格 | 1401033-86-0 生产商 | 订单 1401033-86-0 | 1401033-86-0 代理商|buy AMG-925 | AMG-925 Supplier | purchase AMG-925 | AMG-925 cost | AMG-925 manufacturer | order AMG-925 | AMG-925 distributor | buy 1401033-86-0| 1401033-86-0 Supplier | purchase 1401033-86-0 | 1401033-86-0 cost | 1401033-86-0 manufacturer | order 1401033-86-0 | 1401033-86-0 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.