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Amitriptyline HCl抑制5-羟色胺受体，去甲肾上腺素受体，5-HT4、5-HT2和sigma 1受体，IC50分别为3.45 nM，13.3 nM，7.31 nM，235 nM和287 nM。
| In vitro | DMSO | 56 mg/mL (178.42 mM) | |
| Water | 13 mg/mL (41.42 mM) | ||
| Ethanol | 56 mg/mL (178.42 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.86 mL | 159.31 mL | 318.61 mL |
| 0.5 mM | 6.37 mL | 31.86 mL | 63.72 mL |
| 1 mM | 3.19 mL | 15.93 mL | 31.86 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.37 mL |
*The above data is based on the productmolecular weight 313.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16404 |
|---|---|
| M. Wt | 313.86 |
| Formula | C20H23N.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 549-18-8 |
| SMILES | CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
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