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Amorolfine hydrochloride是一种吗啉类抗真菌药，可抑制D14还原酶和D7-D8异构酶，这些酶消耗麦角固醇并导致木质甾醇在真菌细胞质细胞膜中积聚。
| In vitro | DMSO | 25 mg/mL (70.63 mM) | |
| Water | 8 mg/mL (22.6 mM) | ||
| Ethanol | 64 mg/mL (180.8 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.25 mL | 141.24 mL | 282.49 mL |
| 0.5 mM | 5.65 mL | 28.25 mL | 56.5 mL |
| 1 mM | 2.82 mL | 14.12 mL | 28.25 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.65 mL |
*The above data is based on the productmolecular weight 354.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10072 |
|---|---|
| M. Wt | 354.0 |
| Formula | C21H36ClNO |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 78613-38-4 |
| Synonyms | Amorolfin, Curanail, Loceryl, Locetar, Odenil |
| SMILES | CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C.Cl |
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