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Amoxapine是一种三环二苯并x氮杂（N-芳基哌嗪），其作用与其他几种三环抗抑郁药相似，阿莫沙平抑制GLYT2a转运活性，IC50为92 μM。
| In vitro (25°C) | DMSO | Warmed: 3 mg/mL (9.56 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+corn oil | 1 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.87 mL | 159.35 mL | 318.69 mL |
| 0.5 mM | 6.37 mL | 31.87 mL | 63.74 mL |
| 1 mM | 3.19 mL | 15.93 mL | 31.87 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.37 mL |
*The above data is based on the productmolecular weight 313.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16406 |
|---|---|
| M. Wt | 313.78 |
| Formula | C17H16ClN3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 14028-44-5 |
| Synonyms | CL-67772 |
| SMILES | C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl |
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