ARRY-380 (Irbinitinib)

目录号: A16413

HER2 抑制剂

ARRY-380 (Irbinitinib)

ARRY-380 (Irbinitinib) Chemical Structure

CAS NO. 937263-43-9

ARRY-380是人表皮生长因子受体酪氨酸激酶ErbB-2(也称为HER2)的口服生物利用抑制剂,具有潜在的抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 287.00
10 mg
¥ 490.00
50 mg
¥ 1,435.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ARRY-380是人表皮生长因子受体酪氨酸激酶ErbB-2(也称为HER2)的口服生物利用抑制剂,具有潜在的抗肿瘤活性。
In vitro DMSO 87 mg/mL (181.05 mM)
Water Insoluble
Ethanol 14 mg/mL (29.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.05 mL 208.11 mL
0.5 mM 4.16 mL 20.81 mL 41.62 mL
1 mM 2.08 mL 10.41 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16413
作用机制 Inhibitor (抑制剂)
M. Wt 480.52
Formula C26H24N8O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 937263-43-9
Synonyms Tucatinib, ONT-380, Irbinitinib
SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5

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