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Ascomycin (FK520)是他克莫司的乙基类似物（FK506），具有强的免疫抑制特性。已经研究出其用于治疗自身免疫疾病和皮肤疾病，并防止器官移植后的排斥反应。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.63 mL | 63.13 mL | 126.26 mL |
| 0.5 mM | 2.53 mL | 12.63 mL | 25.25 mL |
| 1 mM | 1.26 mL | 6.31 mL | 12.63 mL |
| 5 mM | 0.25 mL | 1.26 mL | 2.53 mL |
*The above data is based on the productmolecular weight 792.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15788 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 792.01 |
| Formula | C43H69NO12 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 11011-38-4 |
| Synonyms | Immunomycin, FR-900520, FK520 |
| SMILES | CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C |
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