Ascomycin

Name: Ascomycin
SKU: A12592

目录号: A12592

calcineurin 抑制剂

Ascomycin Chemical Structure

CAS NO. 104987-12-4

Ascomycin是一种有效的免疫抑制剂，可用作自身免疫性疾病的潜在治疗剂。

库存：现货

规格	价格	数量
10 mg	￥ 175.00
25 mg	￥ 280.00
10mM * 1mL in DMSO	￥ 2,905.00

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生物活性

Ascomycin是一种有效的免疫抑制剂，可用作自身免疫性疾病的潜在治疗剂。

靶点信息

calcineurin phosphatase
49 nM

溶解度 *

In vitro	DMSO	98 mg/mL (123.73 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (123.73 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.63 mL	63.13 mL	126.26 mL
0.5 mM	2.53 mL	12.63 mL	25.25 mL
1 mM	1.26 mL	6.31 mL	12.63 mL
5 mM	0.25 mL	1.26 mL	2.53 mL

*The above data is based on the productmolecular weight 792.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12592
作用机制	Inhibitor (抑制剂)
M. Wt	792.01
Formula	C43H69NO12
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	104987-12-4
Synonyms	FK 520, FR 900520, FK520, FR900520
SMILES	CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C