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Asenapine hydrochloride抑制肾上腺素能受体（α1，α2A，α2B，α2C）的Ki为0.25-1.2 nM，还抑制5-HT受体（1A，1B，2A，2B，2C，5A，6、7），Ki为0.03- 4.0 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.03 mL | 155.17 mL | 310.34 mL |
| 0.5 mM | 6.21 mL | 31.03 mL | 62.07 mL |
| 1 mM | 3.1 mL | 15.52 mL | 31.03 mL |
| 5 mM | 0.62 mL | 3.1 mL | 6.21 mL |
*The above data is based on the productmolecular weight 322.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15002 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 322.23 |
| Formula | C17H17Cl2NO |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1412458-61-7 |
| Synonyms | Saphris hydrochloride |
| SMILES | CN1CC2C(C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24.Cl |
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