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ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist, with EC50 values of 7.12 nM, 517 nM for hS1P1 and hS1P3, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.18 mL | 85.92 mL | 171.84 mL |
| 0.5 mM | 3.44 mL | 17.18 mL | 34.37 mL |
| 1 mM | 1.72 mL | 8.59 mL | 17.18 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
*The above data is based on the productmolecular weight 581.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18432 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 581.93 |
| Formula | C26H26ClF6NO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1228580-11-7 |
| Synonyms | ASP 1126, ASP-1126 |
| SMILES | O=C(C1CCN(CC2=CC3=CC=C(OCC4=CC=C(OCC(F)(F)F)C(C(F)(F)F)=C4)C=C3OC2)CC1)O.[H]Cl |
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