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Atazanavir sulfate (BMS-232632-05)

Atazanavir sulfate (BMS-232632-05)

Name: Atazanavir sulfate (BMS-232632-05)
SKU: A10096

目录号: A10096

HIV Protease 抑制剂

Atazanavir sulfate (BMS-232632-05) Chemical Structure

CAS NO. 229975-97-7

Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂（PI）类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 315.00
10 mg	￥ 420.00
25 mg	￥ 630.00
50 mg	￥ 840.00
10mM * 1mL in DMSO	￥ 462.00

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生物活性

Atazanavir sulfate (BMS-232632-05)是蛋白酶抑制剂（PI）类的抗逆转录病毒药物。是一种高选择性的 HIV-1蛋白酶抑制剂。

靶点信息

HIV protease (Cell-free assay)
2.66 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	92 mg/mL (114.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.45 mL	62.27 mL	124.55 mL
0.5 mM	2.49 mL	12.45 mL	24.91 mL
1 mM	1.25 mL	6.23 mL	12.45 mL
5 mM	0.25 mL	1.25 mL	2.49 mL

*The above data is based on the productmolecular weight 802.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10096
作用机制	Inhibitor (抑制剂)
M. Wt	802.9
Formula	C38H52N6O7.H2SO4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	229975-97-7
Synonyms	BMS-232632-05, CGP-73547, Reyataz, Zrivada
SMILES	CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O