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Atglistatin是一种高效,选择性和竞争性的甘油三酸酯脂肪酶(ATGL)抑制剂,IC50约为0.7μM,可在体外抑制脂解,但浓度达50μM时无毒性。
In vitro | DMSO | 55 mg/mL (194.09 mM) | |
Water | Insoluble | ||
Ethanol | 4 mg/mL (14.11 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 35.32 mL | 176.58 mL | 353.16 mL |
0.5 mM | 7.06 mL | 35.32 mL | 70.63 mL |
1 mM | 3.53 mL | 17.66 mL | 35.32 mL |
5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
*The above data is based on the productmolecular weight 283.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13814 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 283.16 |
Formula | C17H21N3O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1469924-27-3 |
SMILES | CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C |
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